A team has demonstrated in mouse models that a self-assembling nanofibre material could limit the damage caused by cytokines in inflammatory diseases.
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A team has created a biosynthetic pathway for E. coli that allows the bacteria to produce a common arthritis drug.
A molecule called TPPU has been shown to inhibit an enzyme that plays a key role in inflammation, successfully treating arthritis in mice.
Researchers observed that deleting the IRE1-alpha gene caused beta cells to de-differentiate and then re-differentiate in mice, preventing immune system auto-activation.
CMPK2 inhibitors may reduce inflammation, pain and tissue damage in arthritis and gout and in Alzheimer’s may slow loss of cognitive function...
Scientists have discovered that itaconate - a molecule derived from glucose - acts as a powerful off-switch for macrophages...
A research team has discovered the process - and filmed the actual moment - that can change the body’s response to a dying cell.
Scientists have discovered a molecule that enhances cartilage regeneration and decreases inflammation.
Researchers have found a pattern of genes which is characteristic of osteoarthritis and may be a step towards better treatments for this condition.
The first drug to treat calcification of heart valves may be one originally designed for rheumatoid arthritis.
Researchers from UPM and CSIC have employed waste from the agri-food industry to develop biomaterials that are able to act as matrices to regenerate bone and cartilage tissues, which is of great interest for the treatment of diseases related to ageing.