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The effect of temperature and humidity on the number of cases and deaths of COVID-19 all over the world
Sarah Ahmed explores how environmental factors may be causing the disparity in numbers of cases between different countries.
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Covid-19
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Antibodies against viral disease: highlighting technologies behind COVID-19 antibody therapy
Amid the rush to develop an effective vaccine against COVID-19, antibody therapy has become a major strategy to ameliorate and treat cases of severe disease. Armed with the capacity to neutralise pathogens and orchestrate the immune system, promising antibody candidates for multiple viral indications, including HIV, continue to emerge. Technology…
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Delivering a therapy to kerb COVID-19
Sheraz Gul explores current research developments to help treat and tackle the spread of COVID-19.
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If Columbus had a map… guiding the discovery of new drugs
Exploring large databases and selecting compounds of interest can be extremely time-consuming for researchers. Here, Sacha Javor, Horst Flotow and Jingwen Shi discuss a novel chemoinformatics approach for drug discovery.
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Researchers identify 27 biomarkers of COVID-19 disease severity
Mass spectrometry revealed biomarkers that could be used as drug targets for developing novel therapeutics or to predict whether a patient with COVID-19 will become severely ill.
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Mapping SARS-CoV-2 infection in the airway
Researchers found there is a gradient of SARS-CoV-2 infectivity down the airway and that the severe pneumonia symptoms may be caused by aspiration of oral contents into the lungs.
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Using scientific literature to aid the development of a safe and effective COVID-19 vaccine
Researchers in the US describe how they utilised previously published scientific literature to guide the design of their potential COVID-19 vaccine.
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SARS-CoV-2 mouse model recapitulates human infection
Researchers develop a knock-in mouse expressing human angiotensin-converting enzyme 2 (hACE2) to model SARS-CoV-2 infection for research and therapeutic or vaccine testing.
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Using pharmacologically-established medicines to treat COVID-19
A new suggestion has highlighted that the available pharmacologically-established existing medicines should be used to combat COVID-19.
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Free to view detailed 3D models of SARS-CoV-2 unveiled
Collaboration between scientists, illustrators and simulators has culminated in highly detailed three-dimensional (3D) models of SARS-CoV-2.
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Chemical formulas relevant to COVID-19 drug targets
Find several chemical formulas for potential COVID-19 therapeutics and drug targets currently in development here.
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Blood test could identify those most at risk from COVID-19
Collaborative research has revealed two hallmarks of COVID-19 infection associated with more severe symptoms that can be identified by a blood test.
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White blood cells as a novel early indicator of vaccine efficacy
Researchers demonstrate that a subpopulation of circulating white blood cells can act as an early indicator of vaccine efficacy, with potential implications for COVID-19 drug development.
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Protective immunity to SARS-CoV-2 shown in non-human primates
Macaques were protected against SARS-CoV-2 infection both after an initial infection and vaccination with a prototype vaccine, researchers suggest humans could respond similarly.
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Human enzymes could be driving COVID-19 evolution, suggest researchers
Post-infection genome editing could be the cause of mutations in the SARS-CoV-2 virus responsible for the COVID-19 pandemic, driving its evolution.
