Researchers have developed a 'scar in a dish' model derived from human stem cells which mimics the progressive scarring that occurs in human organs and has lead to a drug candidate being identified to stop the progression of fibrosis.
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Researchers have developed a new AI system which was able to discover and then successfully test several new compounds within 46 days.
Despite being one of the more ancient aspects of immunity, therapeutic modulation of the innate immune system has rarely been attempted. Innate immunity is intrinsically linked to the generation of inflammation – necessary for signalling to the adaptive immune system but often self-perpetuating and over-exaggerated, leading to deleterious effects, including…