A collaboration of academic institutions in the United States has identified a gene that is linked to alternative splicing changes that occur in several cancers.
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Research indicates that activation of the RICTOR/mTORC2 pathway advances cancer metastasis and suggests that inhibiting this signalling may make chemotherapy more effective against colon cancer.
PPP2R2A gene allele deletion in prostate cancers promotes the uncontrolled division of cells, reinstatement of its protein causes cancer cell death, so could provide a new therapeutic option.
Researchers have developed a cell line that allows the mechanisms of prostate cancer bone metastasis to be studied in immunocompetent mice.
A chaperone protein has been identified as a possible therapeutic target for the treatment of Kennedy's disease and prostate cancer.
Researchers have discovered a non-coding RNA which could be used as a biomarker and in new therapies for prostate cancer.
In a recent study more than half of patients with advanced prostate cancers appear to be strong candidates for targeted cancer therapies.
Identified using a computer algorithm, the NSD2 gene may be responsible for advancing the spread of prostate cancer, and so could be used as a drug target...
Researchers in the US have discovered how a gene involved in regulating hormone receptors, GREB1, may contribute to drug resistance in some prostate cancer patients.
Scientists in the U.S. have developed molecules, termed cyclic peptoids, that block the action of genes that drive the growth of therapy-resistant prostate cancer, according to a new study.
Researchers are developing an antibody-based approach to destroy deadly ovarian cancer -- an approach that could also be modified to kill breast, prostate and other solid tumours...
Tumours with alterations in the CDK12 gene were more responsive to immunotherapy, suggesting precision medicine approach...
Cancer researchers have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers...
A test of contrast-enhanced subharmonic imaging has shown promise in detecting prostate cancers that were not identified by MRI...
Scientists have discovered that cells lacking the tumour-suppressor protein PTEN – a feature of many cancers – are particularly vulnerable to drugs that impair their energy-producing mitochondria.