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Imaging

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Chemists develop Washington Red dye for bio-imaging

11 December 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have created an injectable dye that illuminates molecules with near-infrared light...

news

How an incidental exhalation led to improved DNA detection device

8 December 2017 | By Drug Target Review

While attempting to position two chips on a microscope, an involuntary exhalation by scientist Greg Madejski caused them to adhere to great effect.

news

Innovative probe visualises tumours

8 December 2017 | By Drug Target Review

A new probe has the potential to help surgeons visualise primary non-fluorescing, low-grade gliomas during surgery to remove the tumour.

news

UV light microscope proves useful diagnostic tool

6 December 2017 | By Drug Target Review

Recent study shows how a microscope using ultraviolet (UV) light to illuminate samples enables pathologists to assess high-resolution images of biopsies and other fresh tissue samples for disease, quickly and effectively.

article

Drug Target Review – Issue #4 2017

5 December 2017 | By Drug Target Review

Issue 4 of Drug Target Review looks at artificial intelligence in drug discovery and features In-Depth Focuses on Screening, Hit to Lead and Informatics.

Scientists visualise structure of key DNA repair component

news

Scientists visualise structure of key DNA repair component

1 December 2017 | By Drug Target Review

The ATR protein has been imaged at ‘near-atomic resolution’, providing greater insight into its activation in DNA repair.

news

Structure of primary optogenetic tool identified

28 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have determined the 3-D structure of channelrhodopsin 2, a membrane protein widely used in optogenetics to control nerve cells with light...

news

fMRI-neurofeedback shows promise in treating tinnitus

27 November 2017 | By Dr Zara Kassam (Drug Target Review)

By using functional MRI researchers have found that neurofeedback training has the potential to reduce the severity of tinnitus or even eliminate it...

news

AFM-CRISPR technique used to map DNA mutations

21 November 2017 | By Dr Zara Kassam (Drug Target Review)

Nanomapping technology may transform the way disease-causing genetic mutations are diagnosed and discovered...

news

Mn-PyC3A MRI contrast agent may be a safer alternative to gadolinium

16 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a potential alternative to gadolinium-based contrast agents for magnetic resonance imaging...

news

Next-generation optogenetic molecules control single neurons

14 November 2017 | By Dr Zara Kassam (Drug Target Review)

Focused laser beam could help scientists map connections among neurons that underlie behaviour...

Scientists create “tracking” nanoagents to illuminate very small diseased tissues

news

Scientists create “tracking” nanoagents to illuminate very small diseased tissues

9 November 2017 | By Drug Target Review

Polymer nanoagents that can ‘light up’ tiny areas of diseased tissues that conventional methods fail to detect, have been created by a research team led by NTU Singapore.

news

FDG PET shows tumour DNA levels in blood are linked to NSCLC

8 November 2017 | By Dr Zara Kassam (Drug Target Review)

Insights derived from FDG PET could improve treatment selection for patients with advanced non-small cell lung cancer...

news

Cryo-electron microscopy used to identify CPF protein structure

30 October 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have used cryo-electron microscopy to solve the structure of a protein complex critical for gene expression...

news

Fluorescent imaging with cetuximab safely used in glioblastoma patients

25 October 2017 | By Dr Zara Kassam (Drug Target Review)

Antibody-based infrared fluorescent imaging can specifically distinguish cancer from normal tissue in patients with glioblastoma...

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Imaging