Screening

Application note: Automated Extraction of High Molecular Weight DNA

14 November 2019 | By Analytik Jena

SmartExtraction significantly simplifies the entire automated workflow of DNA extraction.

New vaccine protects from widespread, costly infection

14 November 2019 | By Rachael Harper (Drug Target Review)

A new vaccine against the Staphylococcus aureus infection has proven effective in experiments with mice, with an 80 percent survival rate.

Application note: Multiplex Fluorescent Western Blot Detection

13 November 2019 | By Analytik Jena

Challenge: One touch imaging of multiple proteins on the same blot with NIR fluorescent tags. Solution? Automated imaging with the UVP ChemStudio.

eBook: Simple as a Selfie: One-Button Scientific Imaging

13 November 2019 | By Analytik Jena

Proper signal visualization, detection, and quantification are paramount to the acquisition of accurate and reproducible data...

Application note: In Vivo Imaging with GFP

12 November 2019 | By Analytik Jena

Challenge: Non-invasive imaging of a patient-derived orthotropic mouse model of pancreatic cancer expressing GFP. The solution? In vivo imaging.

eBook – Getting the Inside Story: In Vivo Imaging

12 November 2019 | By Analytik Jena

In vivo imaging has been an indispensable and powerful tool in biomedical research, enabling a number of significant breakthrough discoveries.

Analytik Jena

Liver-Chip used to study toxicity of drug candidates

7 November 2019 | By Victoria Rees (Drug Target Review)

Researchers have made a ‘Liver-Chip’ which is able to demonstrate the toxic effects of drug candidates and compounds in human patients.

Study aims to boost antitumoral activity of compound in Amazon plant

1 November 2019 | By Rachael Harper (Drug Target Review)

Scientists seek to design therapeutically more potent chemicals from alkaloids produced by the plant, Uncaria guianensis, which could aid in combatting tumours.

Application note: Reliable Single Cell Cloning with Advanced Microfluidic Dispensing

24 October 2019 | By Sphere Fluidics Ltd.

Find out how to accelerate and improve selective single cell cloning with advanced microfluidic dispensing.

Machine-learning algorithm developed to aid in epigenetic drug discovery

23 October 2019 | By Rachael Harper (Drug Target Review)

A machine-learning algorithm has been created that automates high-throughput screens of epigenetic medicines.

New horizons in small molecule solubility screening

22 October 2019 | By Halo Labs

Aqueous solubility of small molecule compounds is an essential parameter during the hit-to-lead stage of drug discovery as well as lead optimization and formulation. Low solubility can result in misleading ADMET/DMPK analyses if some fraction of a compound precipitates. Watch on-demand to find out more!

CRISPR RNA-cutting enzyme programmed to kill viruses in human cells

14 October 2019 | By Rachael Harper (Drug Target Review)

Researchers have developed CRISPR-Cas13 enzyme-based technology that can be programmed to both detect and destroy RNA-based viruses in human cells.

3D tissue models of brain tumours created in brain-mimicking environment

11 October 2019 | By Rachael Harper (Drug Target Review)

A new platform has the potential to better understand what dictates the invasive behaviour of brain tumours.

New compound keeps cells alive and functioning in a healthy state

7 October 2019 | By Rachael Harper (Drug Target Review)

A world-first compound that can keep cells alive and functioning in a healthy state could be revolutionary for medical emergencies.