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Cell survival mechanisms identified through RNA regulation in central nervous system
A new study from Niigata University has found a binding protein that is vital for proper development of the central nervous system.
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Stem Cells
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Pre-clinical study shows significant increase in effectiveness of breast cancer immunotherapy
Scientists have discovered the essential role of a ligand-dependent corepressor to potentially enable cancer cells to present tumour antigens on their surfaces.
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“Monumental” step in using human iPSCs towards treating complication of diabetes
A new study led by the Indiana University School of Medicine showed human induced pluripotent stem cells can improve visual acuity, vascular health and other complications related to type 2 diabetes.
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Scientists have shown ageing process can be safely and effectively reversed in mice
New research by the Salk Institute has shown cellular rejuvenation therapy safely reverses signs of ageing in mice.
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Molecular pathway shared by two neurodegenerative disorders found
Scientists have gained deeper knowledge about the mislocalisation of a protein, providing a possible therapeutic target that could have implications in treating dementia.
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Ncardia appoints Andy Holt as Chief Commercial Officer
An iPSC technology leader taps industry veteran to drive growth in cell therapy and drug discovery markets.
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Study identifies key regulator of cell differentiation
Long-awaited findings about cell differentiation will be relevant in understanding normal development and may also be useful in cancer research.
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Breakthrough method developed to grow model organs
Researchers have successfully generated organoids in suspension, offering the possibility of larger-scale experiments to study human development and disease.
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Scientists ‘reinvent’ petri dish for growing live brain tissue
Researchers have innovated the petri dish to be able to grow and age live brain cells from patients with neurological disorders.
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Game-changing model to identify drugs that may slow AMD
Researchers have identified potential age-related macular degeneration drugs using a novel stem-cell based research tool.
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Bone marrow stem cell transfusions show promise as potential treatment for sepsis
New research has shown that one-time infusion of stem cells from bone marrow improves the survival of mice with sepsis.
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Engineered airway lining created to study how COVID-19 affects respiratory tracts
Researchers have made a respiratory model of COVID-19, made from patient-derived stem cells, to understand how the virus affects respiration and which could be used to test possible drugs.
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Model to study oculocutaneous albinism eye conditions developed
The first patient-derived stem cell model to research eye conditions related to oculocutaneous albinism (OCA) has been created.
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New model yields promising gene therapy for heart condition
Scientists in Japan have developed a credible heart cell model for arrhythmogenic cardiomyopathy and observed a positive response in the condition using PKP2 gene therapy.
whitepaper
Whitepaper: How to successfully use iPSCs for disease modelling
Benefits and key considerations of using human iPSC-derived disease models in drug discovery.
