microRNA could lead to new methods to treat multiple sclerosis
In a pre-clinical model of multiple sclerosis, orally treating susceptible mice with a microRNA from the diseased gut has prevented the disease.
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Researchers find mutation in CUL3 gene responsible for autism
Scientists have shown that the mutated CUL3 gene, which is involved in the cell’s clearance of proteins, plays a role in the development of autism and schizophrenia in mice.
MAIT immune cells revealed as key in toxic shock development
Researchers have found that MAIT immune cells respond rapidly to group A streptococcal infection, causing inflammation and toxic shock, which presents a therapeutic target.
New approach to treating incurable leukaemia in children discovered
A new study into the molecular causes of acute lymphoblastic leukaemia could lead to a new target for therapy.
Normal liver cells may have the potential to kill cancer cells
A new discovery that healthy liver tissue surrounding a tumour activates a defence mechanism that restrains tumour growth could inspire new therapeutic approaches that mobilise normal cells to kill cancer cells.
Tendon stem cell discovery could lead to improvements in injury recovery
Researchers have discovered the existence of tendon stem cells, which could lead to improvements in treating tendon injuries, avoiding surgery.
Researchers discover potent new antimicrobial molecule
A compound that has antimicrobial properties has been found by researchers, which could be used to combat drug-resistant infections.
New insights into blood clot mechanisms in cancer patients discovered
A new signalling pathway has been identified that may help further the understanding of blood clot formation in cancer patients and presents a new drug target for reducing cancer-associated complications.
Mucin 6 gene indicates predisposition to late-onset Alzheimer’s
Scientists have idenified that variation in a gene called Mucin 6 appears to indicate a tendency for acquiring Alzheimer’s disease.
Inflammatory regulatory protein identified by researchers
A study has discovered that the PKM2 protein plays a role in regulating immune cells and blocking this could be a potential treatment for inflammatory diseases.
Lung response to bacteria revealed by researchers
A study has discovered the process behind the lung immune response, which could be used to develop treatments against pneumonia.
Faster 3D imaging possible with novel microscopy approach
A novel imaging approach has been developed which could lead to new discoveries in biology and medicine.
Novel peptide could lead to antibiotic for drug-resistant bacteria
A novel peptide has been discovered that attacks gram negative bacteria at a previously unknown site of action which presents a promising lead substance for the development of a new antibiotic.
Major step taken in creating complex organs in the lab
A major step has been taken towards developing functional miniature versions of human organs in a Petri dish which can be used to shed light on the processes involved in the genesis of diseases.
Experimental HIV vaccine induces bnAb production in models
Researchers have developed a vaccine for HIV that has shown success in rabbits, by neutralising a wide range of HIV strains using bnAbs.
