Molecules associated with NMDAR may be involved in schizophrenia
Genetic variants which prevent a neurotransmitter receptor from working properly have been implicated in the development of schizophrenia...
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ADM-RAMP2 system could be therapeutic target for retinal vein occlusion
Researchers suggest that the retinoprotectivity of the ADM-RAMP2 system makes it an ideal therapeutic target for central retinal vein occlusion (CRVO)...
Scientists developed a new mouse model of Hirschsprung’s disease
Researchers have developed the first viable mouse model of Hirschsprung’s disease and associated enterocolitis with a defect in GDNF/GFRa1/RET signalling...
Perfect human blood vessels grown in petri dish
Researchers have been able to grow perfect human blood vessels in the lab, and are now looking to conduct disease research for vascular diseases...
GREB1 gene potential drug target for prostate cancer treatment
Researchers in the US have discovered how a gene involved in regulating hormone receptors, GREB1, may contribute to drug resistance in some prostate cancer patients.
Neurons made from skin cells are valid when studying disease
A study has found that using skin cells and transforming them into neurons is a valid approach to study neurodegenerative diseases such as Parkinson's...
Potential therapeutic target for ALS revealed
Strathmin2 could be used as a biomarker for amyotrophic lateral sclerosis (ALS), a debilitating condition with no proper diagnostic tests or treatments...
CRISPR/Cas9 shown to limit impact of certain parasitic diseases
Researchers successfully used CRISPR/Cas9 to limit the impact of schistosomiasis and liver fluke infection...
Producing vaccines without the use of chemicals
Innovative new technology will use electron beams to produce inactivated vaccines quickly, reproducibly and without the use of chemicals...
Stopping inflammation using a molecular switch
A component in the ubiquitin system has been described as being able to deactivate the innante immune system and could help to prevent immune conditions...
Engineered T-cells promote acceptance of organs after transplant
Controlling coronin 1 in T-cells could lead to the immune system not attacking transplanted organs, but still fighting other infections...
Using the SVM method to predict enhancers from tissues and cell lines
A team of researchers have developed a computational bioinformatic method to predict and accurately locate enhancer regions on cell lines.
CRISPR repurposed to develop better antibiotics
Mobile-CRISPRi could be used to guide gene expression, in turn control levels of proteins produced, enabling scientists to identify key antibiotic targets...
New therapeutic concept controls pathogenic T-cells relevant in MS
Researchers have identified an innovative and promising therapeutic option to treat multiple sclerosis...
Hidden culprit in heart failure discovered
A study has identified that PI3K alpha could be the culprit of heart failure, as it binds to gelsolin, suppressing it and preventing it from working...
