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What is the link between serotonin and heart valve disease?

3 February 2023 | By Izzy Wood (Drug Target Review)

US researchers found that serotonin impacts the mitral valve in the heart which can lead to heart valve disease.

news

FDA clears Cellenkos IND application for potential ALS treatment

20 October 2022 | By Victoria Rees (Drug Target Review)

Following FDA clearance, Cellenkos will initiate Phase I and Phase Ib trials of CK0803, allogeneic regulatory T cells, in patients with ALS.

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Researchers plan to image every cell in the human brain at unprecedented speed

12 April 2022 | By Ria Kakkad (Drug Target Review)

Columbia-led team wins research grant to create fundamentally new maps that will chart cell diversity throughout the brains of humans.

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Flaw found in lab models used to study human blood-brain barrier

8 February 2021 | By Victoria Rees (Drug Target Review)

Researchers have uncovered a flaw in lab models used to study the human blood-brain barrier and a potential strategy to correct the error.

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Scientists propose treating SARS-CoV-2 with sofosbuvir and remdesivir

7 October 2020 | By Victoria Rees (Drug Target Review)

Researchers have posited that SARS-CoV-2 could be combatted by sofosbuvir, in combination with other antivirals such as remdesivir.

news

First images of an ‘upgraded’ CRISPR tool captured

20 December 2019 | By Drug Target Review

Researchers have utilised cryo-electron microscopy and used the images they captured with an electron microscope to generate atomic resolution models of the INTEGRATE system.

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Transplanted stem cells used to grow functional lungs in mice

8 November 2019 | By Victoria Rees (Drug Target Review)

Researchers have revealed that stem cells transplanted into embryonic mice can mature into fully functional lungs, a method which could be developed to grow lungs for humans.

article

Uniting humans and data: the role of AI in genomics

27 August 2019 | By Victoria Rees (Drug Target Review)

AI has applications in many areas of research, including genomics. Slavé Petrovski of AstraZeneca reveals how AI is used in the study of the human genome and how it may evolve in the future.

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Behaviour of mouse’s brain controlled with single-cell precision

4 July 2019 | By Drug Target Review

Researchers prove it's possible to control a visual behaviour of a mouse by activating neurons in its visual cortex.

news

New technology provides process for precise gene editing

13 June 2019 | By Victoria Rees (Drug Target Review)

Researchers have presented their new technology for accurately inserting genes into the genome without cutting DNA.

news

Scientists decipher 3D structure of promising molecular target for cancer treatment

5 April 2019 | By Drug Target Review

Columbia University discovery could be a major step in developing therapies for cancer, controlling cholesterol...

news

Kidney disease biomarker could help detect COPD

28 September 2018 | By Iqra Farooq (Drug Target Review)

A biomarker usually used with kidney disease, could potentially be used to detect COPD through identifying levels of albuminuria in urine...

news

Profiling the genome hundreds of variations at a time

24 May 2018 | By Drug Target Review

A CRISPR-Cas9 high-throughput strategy creates the possibility to rapidly profile and identify genes and DNA sequence variations key to different traits and diseases.

news

CRISPR used to restore retinal function

14 May 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a new technique to restore retinal function in mice afflicted by a degenerative retinal disease, retinitis pigmentosa...

news

Cell therapy aids heart recovery

25 April 2018 | By Dr Zara Kassam (Drug Target Review)

Biomedical engineers invent an innovative technique to help injured hearts regenerate...

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