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University of California Los Angeles (UCLA)
A new study shows that gene therapy could correct a rare creatine deficiency disorder that commonly results in intellectual disabilities, problems with speech, involuntary movements, and recurrent seizures.
Scientists have successfully created viable organoids from tumour samples from five patients with a rare bone cancer called a chordoma, which has few therapeutic options.
This article delves into research at the University of California Los Angeles, US, where stem-cell derived brain organoids that can mimic electrical activity have been developed.
Study shows that removing the protein IGF2BP3 slows cancer growth and increases chances of survival of rare types of leukaemia in mice.
Monoamine oxidase inhibitors can block the function of a protein, helping T cells to effectively fight cancer, a study in mice has shown.
Researchers have developed a stem cell therapy that could treat the damage caused by dementia by launching a repair response.
Inhibiting the KDM4A enzyme slowed the growth of head and neck cancer in mouse models, also demonstrating promise to aid immunotherapy.
A combination of chemicals has shown promise in pre-clinical studies to produce muscle stem cells, giving hope for regenerative medicine.
A collaboration of academic institutions in the United States has identified a gene that is linked to alternative splicing changes that occur in several cancers.
Researchers have developed a 'scar in a dish' model derived from human stem cells which mimics the progressive scarring that occurs in human organs and has lead to a drug candidate being identified to stop the progression of fibrosis.
Researchers have created a new high-throughput screening system which could identify new drugs by focusing on nucleotide metabolism.
Researchers have identified that Alexidine dihydrochloride can be used as a broad spectrum antifungal, and can also kill biofilms formed by these fungi...
Using a unique in vitro method, scientists in California have made inroads into understanding the mechanics of the polygenic origins of schizophrenia...
Researchers discovered effective antibiotic combinations using four or five drugs, despite claims that combinations of three or more won't work...