Combining two genomic methodologies, researchers have shown that pancreatic exocrine cells are implicated in type 1 diabetes.
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University of California San Diego
A new gene therapy that introduced SynCav1 to the brains of Alzheimer's mouse models was shown to preserve neuronal and synaptic plasticity.
In pre-clinical studies, a novel treatment decreased plaque formation, meaning it could be used to prevent Alzheimer's disease.
An antisense oligonucleotide has been developed by researchers to inhibit IRF4 as a potential strategy to treat multiple myeloma.
Human genome-produced RNA has been found on the surface of human cells, which researchers say could be easier for therapeutics to reach.
Researchers have shown that a mutation in the n-Tr20 gene can alter brain function and behaviour, while loss of the gene made mice resistant to seizures.
By administering a one-time PTB antisense oligonucleotide therapy to mice, researchers observed an increase in neurons and elimination of Parkinson's from the models.
Researchers have developed 'nanosponges' cloaked in lung cell membranes and macrophage membranes which they found could attract and neutralise COVID-19 in cell cultures.
Scientists in the US have applied a novel technique to finally unravel a particular kinase enzyme that is associated with familial Parkinson’s disease; providing a clearer potential therapeutic target.
Researchers have developed a novel metal-based fragment library of molecules that can be used to screen for new drug candidates.
A study has revealed that the mitoNEET protein controls a metabolic and functional gateway on mitochondria, which could provide a drug target for cancer.
Scientists have detailed the role of a key controlling factor in the transformation of B-cells into antibody-secreting cells.
The detection of 'copy editing' by a stem cell enzyme in over 20 tumour types could be a biomarker and possible therapeutic target for certain cancers...
An international team of scientists has developed a candidate identification technique in the form of an algorithm that reduces the chances of rediscovering known compounds.