A study out of Japan reveals diversity of protein structures and how they fold in nature, uncovering a myriad of protein topologies.
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Swiss researchers have achieved near-perfect control over the manipulation of individual DNA molecules, allowing them to be identified and characterised with unprecedented precision
US study uncovers the best way to treat recurrent or progressive brain metastases using an amino acid PET technique.
Researchers from Switzerland identify peptides that detect and measure a key biomarker in inflammatory conditions.
As new variants of the SARS-CoV-2 virus emerge, leading scientists Dr Oscar Bastidas and Dr Zoran Sevarac explore how their latest research identified a structured frequency domain profile in data with no discernible pattern. Their article also emphasises that it remains imperative to continue learning about this pathogen’s molecular machinery…
Researchers have streamlined the traditionally slow process of enzyme engineering. This work might help researchers tailor the suitability of enzymes for custom purposes.
Product hub: High-throughput screening of cyclic peptide libraries for developing drugs to challenging targets
Professor Christian Heinis explains how peptides could offer the next generation of therapeutics and what is required to screen libraries of cyclic peptides.
New findings from collaborative research in the United States have identified a promising new treatment avenue for type 2 diabetes patients centring on the activity of the amino acid, GABA.
A team has characterised a key part of the peptide synthesis process, showing that only the main building block needs to be changed for re-engineering.
Researchers have developed a new technique called mim-tRNAseq to measure, map and analyse tRNAs in cells, providing insight into disease.
Researchers have synthesised peptides that function like a soluble chemokine receptor, blocking atherosclerosis in animal models.
Researchers reveal the main protease (Mpro) of SARS-CoV-2 is highly sensitive to disruption, therefore Mpro inhibitors could be a potential COVID-19 therapeutic.
The novel protocol allows proteins over 100 amino acids long to be synthesised in hours and include amino acids that do not occur in the human proteome.
Post-infection genome editing could be the cause of mutations in the SARS-CoV-2 virus responsible for the COVID-19 pandemic, driving its evolution.