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Positive pre-clinical results for CRISPR-based HIV therapy
The CRISPR-based therapy called EBT-101 excised HIV proviral DNA from the genomes of different cells and tissues in human cells and mice.
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Clinical Trials
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New molecule could complement antibiotics to treat pneumonia
Scientists targeted a mouse's own cells using a synthetic molecule called EEZE, presenting a novel way to treat pneumonia.
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Stealth BioTherapeutics reports positive pre-clinical data for ALS candidate
Stealth BioTherapeutic's SBT-272 improved mitochondrial motility in a murine model of amyotrophic lateral sclerosis.
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Oral COVID-19 vaccine reduces transmission in animal model
A new study has suggested that mucosal vaccines may reduce transmission of airborne viruses such as COVID-19 more than injectable vaccines.
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Chemotherapy drug reverses Alzheimer’s symptoms in mice
Axitinib, a common chemotherapy drug, restored memory and cognitive function in mouse models, representing a potential Alzheimer’s treatment.
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Novel class of LPPOs could provide alternative to antibiotics, study shows
Lipophosphonoxins may represent the next generation of antibiotics and can be delivered using a new type of dressing for skin wounds.
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Promising pre-clinical data announced for Parkinson’s drug
Stealth BioTherapeutics reported positive data from a pre-clinical study evaluating SBT-272 in a murine model of Parkinson's disease.
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Club cell factors may reverse immune suppression in tumours
New research has revealed that club cells secret anti-immunosuppressive factors in tumours, potentially revolutionising cancer therapies.
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Intranasal COVID-19 vaccine shown to be effective in animal models
A nasal spray of the COVID-19 Vaccine Oxford/AstraZeneca was found to protect hamsters and monkeys against SARS-CoV-2 in an NIH study.
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Signalling pathway identified as target against paediatric glioma
Researchers have found a vulnerability in a developmental signalling pathway, presenting a target for paediatric low-grade glioma formation.
webinar
Accelerating drug discovery using novel screening technologies
19 August 2021 | By 10X Genomics
Explore the latest developments in screening technologies and how drug discovery has changed during the past decades in our webinar with 10X Genomics.
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Triple drug combination shows promise for pancreatic cancer treatment
MIT researchers have shown that a combination of three drugs can eliminate pancreatic tumours in mice, possibly leading to new therapies.
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Therapeutic target for aggressive cancers discovered through CRISPR
The RNA-modifying protein METTL1 could be targeted to treat some types of aggressive cancers, including brain, blood and kidney.
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Masitinib found to be an effective COVID-19 treatment in mouse model
Scientists from the University of Chicago discovered that the drug masitinib inhibits the replication of SARS-CoV-2 in mice.
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