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Gene therapy to reduce deafness in mice
Gene therapy has been used to restore hearing in an adult mouse model of DFNB9 deafness, one of the most frequent cases of congenital genetic deafness...
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Drug Discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
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Fighting HIV using anti-cancer immunotherapy
Researchers have used immunotherapy treatments, ordinarily used to treat cancer, to reveal the virus in the cells of people living with HIV...
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Light-based production of drug discovery molecules
Researchers have developed a method of using photocathodes and photoanodes to catalyse reactions that turn organic molecules into drug discovery ones...
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How the immune cell ‘Iron Man’ helps T-cells fight infection
The Iron Man of immune cells, the CD4 cell, has been found to help T-cells fight viral infections, with a lack of these cells often leading to illness...
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CRISPR gene editing could make stem cells ‘invisible’ to the immune system
Stem cells that can be manufactured more efficiently and are 'invisible' to the immune system could prevent the rejection of stem cell transplants...
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Neuromelanin-sensitive MRI could measure biomarker for psychosis
A specific type of MRI, neuromelanin-sensitive magnetic resonance imaging, could lead to the measurement of a psychosis biomarker...
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Simple mechanism that ensures bacterial resistance
The team used techniques used by physicists along with highly specialised equipment to investigate deep into the bacterial membrane...
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Immunotherapy and DNA damage repair combo could target lung cancer
Combination therapy with a CHK1 or PARP inhibitor, with an immune checkpoint inhibitor caused the regression of small cell lung cancer in all mice treated...
webinar
Phenotypic screening using iPSC-based human disease biology
18 February 2019 | By Tecan and Ncardia
Ncardia, will discuss the application of human iPSC-derived cell-based assays and high throughput screening for drug discovery and development.
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Live-imaging technique reveals cellular plug for leaky bio barrier
A microscopy assay has shown the repair mechanism involved in the activation of a protein called Rho, used to plug leaky biological barriers in the body...
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Reprogramming stem cells using the measles virus vector
A method has been developed to reprogram stem cells using the measles virus vector, cutting a four-step process to only one stage...
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Reversible antiplatelet therapy fights cancer metastasis and clotting
A novel antiplatelet therapy could help to prevent heart attacks and stroke through preventing the formation of blood clots...
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Development of a gel for liver cell culture on microchips
Hydrogels could be used to build organs on chips to test potential medications, with the aim that they could potentially replace animal studies...
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Efficacy of breast cancer therapy measured using PET imaging
Researchers have developed a method using PET imaging along with 18F-fluorofuranylnorprogesterone to analyse the efficacy of breast cancer treatments...
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Diagnostic technique reveals biomarker differentiating bladder cancer from inflammation
A biomarker that can differentiate between chronic cystitis (inflammation of the bladder) and a non-muscle invasive-type blood cancer could aid diagnosis...
