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‘Activating’ the immune system against cancer
A study has found that the immune system can be harnessed to fight cancer cells in a particularly efficient manner, one also effective in lung cancer...
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Drug Discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
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Whitepaper: Application of CRISPR/Cas to the generation of genetically engineered mice
Learn how the continued development of CRISPR gene editing technologies opens fresh possibilities for in vivo model design.
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Inhalable mRNA could treat lung disease
An inhalable mix of a polymer and mRNA molecules, used to produce luciferase, could be the method of treating lung diseases in the future...
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Editing enzyme could promote tumour suppressor loss
The detection of 'copy editing' by a stem cell enzyme in over 20 tumour types could be a biomarker and possible therapeutic target for certain cancers...
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Triple-negative breast cancer could be treated using experimental treatment
A mouse study has revealed that triple-negative breast cancer could be tackled by using recombinant Tinagl1 in therapy targeting signalling pathways...
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The mysterious functions of the PCSK9 protein
Researchers have described the methods used to build a model of the 'druggable' PCSK9 inhibitor and detailed how it works...
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Potential drug targets found by muting large silent genes
Streptomyces bacteria has been used to identify compounds that could lead to the production of drugs to treat various conditions...
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Drug targets for Dengue, Zika and Ebola viruses
US researchers have identified possible drug targets for Dengue, Zika and Ebola viruses…
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Vaccine could combat opioid addiction and reduce deaths
Researchers have developed a vaccine to combat the opioid epidemic and to prevent deaths, with possible applications of the vaccine in many areas...
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Ebola-fighting protein found in the human body
A study has found that the human protein, RBBP6, helps fight Ebola virus by interfering with the virus replication cycle…
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Ingestible capsule controlled wirelessly could treat diseases
Researchers have designed a drug delivery capsule that can stay in the stomach for up to 1 month, and could sense and treat infections...
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Repurposing wasp venom as antibiotic drugs
Researchers have used wasp venom to create variants of a peptide that is potent against bacteria but nontoxic to human cells...
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Webinar highlights: Recent advances in diagnostics and treatments – from small molecules to cellular therapies
The webinar presented an overview of the pre-clinical milestones, the current status of the global drug pipeline and a description of a number of novel drugs undergoing clinical trials.
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Expert view: Three-dimensional cell cultures as predictive tools in early drug discovery
Three-dimensional cell cultures (spheroids, organoids) are becoming widely used as a new predictive tool in early drug discovery. The use of 3D cell cultures is believed to provide a more physiologically relevant response than monolayer (2D) cell cultures because they closely mimic the extracellular matrix and cell-cell interactions that occur…
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Immunoassay developed to detect small molecules
An immunoassay developed to analyse small molecules has shown 50 times greater accuracy than current systems of analytical techniques...
