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Study identifies novel lupus drug target
Structure of internal regulator molecule identified, presenting lupus drug potential.
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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Strep A vaccine target identified for global use
Researchers use high-throughput DNA sequencing technology to identify a potential vaccine target for Strep A.
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Protein discovery leads to new hyperparathyroidism drug target
A new signalling protein discovery could lead to drug-based therapies to treat hyperparathyroidism.
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Molecule found to boost immune cells leads to new cancer therapy target
A study has identified a molecule which boosts immune cell function and could be used in cancer therapies.
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Study reveals new opportunity for gastrointestinal drug design
A study has shown that the organisation of the gut is broken into functional compartments, improving opportunities for gastrointestinal disorder drugs and oral vaccines.
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New drug target for depression identified
Researchers find key molecule in depression and identify new therapeutic targets.
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Tissue-damaging protein channel identified
Researchers have discovered an acid-activated protein which could stop damage to tissues as a result of stroke and other health issues.
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Cancer-killing combination therapies unveiled with new drug-screening tool
Method IDs which target therapies, inadequately on their own, can be paired up to kill non-responsive cancers...
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New cancer drug targets accelerate path to precision medicine
Researchers used CRISPR technology to disrupt every gene in over 300 cancer models from 30 cancer types and discover thousands of key genes essential for cancer's survival...
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MicroRNA regulates drug tolerance in subset of lung cancers
Newly identified pathway offers promising targets for preventing tumour relapse...
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Cancer vaccine shows promising results in Lynch syndrome
Vaccination with as few as four tumour antigens generated antigen-specific responses, reduced intestinal tumours, and improved survival in a mouse model of Lynch syndrome...
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Machine-learning model to analyse protein sequences
A machine-learning model has been developed to analyse protein sequences, giving an insight to their structure, function and phylogeny...
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Salamander gene partnerships could help spinal cord regeneration
Gene partnerships found in salamander could give insights into how spinal cord injuries and neurodegenerative conditions could be better treated...
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Anthelmintic drug niclosamide repurposed to treat Helicobacter pylori
Researchers have repurposed use of niclosamide to treat Helicobacter pylori cell lines, focusing on how it is effective in infection models...
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Genetic study confirms that numerous genes contribute to Tourette’s syndrome
A meta-analyses of a number of studies has found that variants in numerous genes work together to contribute to Tourette's syndrome...
