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New model found to improve drug development in pre-clinical trials
Researchers have successfully created a multi-organ in vitro model to test toxicity and efficacy of drugs.
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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Study identifies two enzymes which protect tumour cells
Researchers have found an enzyme and its counterpart which inhibit T-cells from attacking tumour cells.
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Longest successful gene expression raises hopes for gene editing therapies
A study has reported that genes delivered to rhesus monkeys are still being expressed four years later.
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Lyme arthritis molecule found, providing treatment opportunity
A new study has identified a key molecule involved in Lyme arthritis which presents options for preventative therapies.
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Experimental treatment for sickle cell disease success
Researchers announce positive pre-clinical results for two sickle cell disease treatment strategies.
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Potential new therapeutic target for Alzheimer’s discovered
New study finds a promising antagonist that blocks specific interaction between the protein apoE and amyloid precursor protein.
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Biomarkers for potential cancer immunotherapy identified
Researchers have found two biomarkers which play a significant role in the invasion of tumours by T-cells.
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Norovirus structure imaged, providing potential for vaccine development
Researchers have been able to image noroviruses, providing significant information for the development of therapeutics.
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Alzheimer’s protein found, suggesting new drug target
Researchers have found a new drug target for Alzheimer’s disease after identifying a facilitating protein.
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Study reveals vulnerability of common pathogenic viruses
Researchers have developed a stabilisation technique for widespread viruses, creating drug opportunity.
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First in vitro lung cancer test launched
A new in vitro lung cancer diagnostic test has been launched by Roche Diagnostics to provide improved detection of cancer.
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Researchers identify chemotherapy-enhancing molecule
A new study has found a small molecule which prevents cancer cells from mutating and becoming resistant to chemotherapy.
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MS treatment potential after condition-causing genes identified
Researchers have found 12 genes which cause MS, creating potential for preventative treatment of the condition.
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Immune cells could be key to tuberculosis treatment, study finds
Researchers have found that certain immune cells aid in fighting tuberculosis bacteria, providing a new drug target.
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Study reveals potential for malaria prevention vaccine
Researchers have identified a novel drug target for the prevention of malaria.
