news
Targeting mitochondria could reduce cancer invasiveness and resistance to radiotherapy
Uncovered details of a molecular pathway in cancer cells could lead to improved treatment...
List view / Grid view
Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
news
CypA enzyme found in breast milk identified as a target for novel breast cancer drugs
Researchers have identified a protein involved in milk production that could ultimately serve as a target for novel therapies to treat breast cancer...
news
Hsp90: Not just a chaperone
Researchers have shown that heat-shock protein 90 acts as a stimulant for exosome release, as well as a protein chaperone...
news
Non-antibiotic drug developed to treat TB
Scientists at The University of Manchester have developed the first non-antibiotic drug to successfully treat tuberculosis in animals...
news
Tau protein disrupts molecular transport in neurons in Alzheimer’s
Researchers have discovered how the tau protein associated with Alzheimer's affects molecular transport and a nucleporin called Nup98...
news
Neutrophil nanosponges soak up rheumatoid arthritis promoting proteins
The neutrophil nanosponges can absorb and neutralise cytokines which play a role in the development of rheumatoid arthritis...
news
Antibody-based approach to destroy deadly ovarian cancer
Researchers are developing an antibody-based approach to destroy deadly ovarian cancer -- an approach that could also be modified to kill breast, prostate and other solid tumours...
news
Scientists discover over 7,000 effective antibiotic combinations
Researchers discovered effective antibiotic combinations using four or five drugs, despite claims that combinations of three or more won't work...
news
Cannabidiol shows sustained effects against depression
Researchers have found that a single dose of cannabidiol in rats with symptoms of depression was highly effective at eliminating symptoms...
article
The changing face in drug discovery
Over the past decade, pharmaceutical industries have contributed enormously to the discovery of new innovative drugs that have saved countless human lives. Discovering new drugs is a complex team sport that requires an intellectual collaboration across many sectors. These advancements provide powerful tools that arm scientists in the quest for…
news
Inhibiting NF-κB improves heart function in Duchenne muscular dystrophy
Breakthrough research has uncovered an unexpected mechanism that underlies cardiomyopathy in DMD...
news
Dectin-1 pathway may be crucial for treating fungal inflammation and pain
Researchers have identified the dectin-1 pathway as being a potential target for the treatment of pain associated with candidiasis...
news
Scientists discover compound for a non-addictive painkiller
Scientists have discovered the chemical compound AT-121, which could soon lead to a painkiller stronger than morphine, but without the side effects...
news
The molecular link between ageing and neurodegeneration
Researchers have described the discovery of a molecular link between ageing and a major genetic cause of both ALS and FTD...
news
Experimental drug targets cancers associated with Epstein-Barr virus
An experimental drug is reported to have potential to treat Epstein-Barr virus related lymphomas by counteracting the cancer-promoting mechanisms of LMP2A...
