news
Antibacterial cannabinoid compound identified by researchers
A study has revealed that the compound cannabigerol (CBG) is effective as an antibacterial in mice, by preventing bacteria from forming biofilms.
List view / Grid view
Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
news
Possible novel cognitive anti-ageing targets identified
Researchers have shown that two epigenetic regulators could be targeted to improve cognitive and behavioural decline in age-related diseases like Alzheimer’s.
news
Coronavirus update: recent developments in vaccine research
Drug Target Review’s round-up of the latest developments in 2019 novel coronavirus (COVID-19 or SARS-CoV-2) therapeutics and vaccines.
article
Why invest in creating a modifiable drug framework?
Drug Target Review spoke with CUE Biopharma’s President and CSO to find out how and why they created the ImmunoSTAT platform and the ways it may benefit drug design in the future.
news
Natural killer cells identified as source of inflammation in rheumatoid arthritis
A study has shown that natural killer cells are linked to the protein GM-CSF, which causes inflammation, indicating a new target for rheumatoid arthritis.
news
Lung cells found to support hibernating breast cancer cells in mice, revealing target
A study has shown that breast cancer cells are protected by healthy cells in the lungs of mice, allowing them to hibernate before growing into tumours.
news
Non-coding RNA may interact with chromatin to control gene expression
The development of an innovative new technology has led researchers to suggest RNA-chromatin interactions may play a role in gene regulation.
news
Depletion and repopulation of microglia could be a future therapy for TBI
Researchers have shown that by effectively resetting the microglia, recovery of mice after a traumatic brain injury (TBI) was improved.
news
RCAN1 gene revealed as regulator of Down syndrome symptom
A study has shown that the RCAN1 gene plays a role in regulating synaptic plasticity, which contributes to a sympom of Down syndrome.
news
ILC2s sensitise pancreatic tumours to PD-1 checkpoint inhibitors in mice
Scientists identify innate lymphoid cells (ILCs) as possible targets for immunotherapies as their activation makes murine pancreatic tumours sensitive to PD-1 checkpoint inhibitors.
news
Utrophin as a novel therapeutic approach for Duchenne muscular dystrophy
Upregulating utrophin using small molecules could be a new therapeutic approach for Duchenne muscular dystrophy (DMD).
news
New laser system developed for stainless imaging of vesicles
Using ultrashort laser pulses to interact with vesicles, researchers have created a novel label-free imaging method.
news
Toll-like receptor could be targeted to treat age-related macular degeneration
Scientists have implicated toll-like receptor 2 (TLR2) in age-related macular degeneration and shown that knocking it out can improve symptoms in animal models.
news
Novel antibiotic compound revealed through artificial intelligence screening
A new antibiotic compound has been identified by researchers who designed a machine-learning algorithm to screen millions of molecules.
news
New worm model could aid in the study of rare disease
A new earthworm model has been developed for the rare disease, x-ALD, which the scientists say could lead to pharmacological targets for the neuronal alterations of the disease.
