news
Novel antibody breaks bacterial biofilms and prevents sepsis in mice
A new monoclonal antibody has been discovered which disassociates bacterial biofilms and stops bacteria from entering into circulation has been tested in mice.
List view / Grid view
Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
news
New gene therapy for Huntington’s demonstrates success in mice
Researchers have developed a new regenerative gene therapy using neurogenic differentiation, which has shown efficacy treating Huntington's disease in mice.
news
Study reveals how immune system handles fungal and viral infections
Researchers have studied how the human body responds to viral infection when already infected by fungi, offering insights into the immune system.
news
3D models developed by researchers to optimise protein design
A computational programme has been created by researchers to aid in the design of proteins for therapeutics, to predict interactions.
news
New T-cell discovery could lead to treatments for both bacterial infections and autoimmune conditions
A novel highly activated form of T cells could be suppressed to treat autoimmune conditions and activated in treating bacterial infections.
news
Boosting natural killer cells in mice with eczema relieves condition
Researchers have found that using IL-15 to boost natural killer cell numbers in mice helps to combat eczema and could be a therapeutic strategy for patients.
news
Infrared light used to improve photodynamic therapy in model tumours
Researchers have developed a compound that can be activated with infrared light to kill cancer cells in model tumours, advancing the possibilities of photodynamic therapy.
news
Antibacterial cannabinoid compound identified by researchers
A study has revealed that the compound cannabigerol (CBG) is effective as an antibacterial in mice, by preventing bacteria from forming biofilms.
news
Possible novel cognitive anti-ageing targets identified
Researchers have shown that two epigenetic regulators could be targeted to improve cognitive and behavioural decline in age-related diseases like Alzheimer’s.
news
Coronavirus update: recent developments in vaccine research
Drug Target Review’s round-up of the latest developments in 2019 novel coronavirus (COVID-19 or SARS-CoV-2) therapeutics and vaccines.
article
Why invest in creating a modifiable drug framework?
Drug Target Review spoke with CUE Biopharma’s President and CSO to find out how and why they created the ImmunoSTAT platform and the ways it may benefit drug design in the future.
news
Natural killer cells identified as source of inflammation in rheumatoid arthritis
A study has shown that natural killer cells are linked to the protein GM-CSF, which causes inflammation, indicating a new target for rheumatoid arthritis.
news
Lung cells found to support hibernating breast cancer cells in mice, revealing target
A study has shown that breast cancer cells are protected by healthy cells in the lungs of mice, allowing them to hibernate before growing into tumours.
news
Non-coding RNA may interact with chromatin to control gene expression
The development of an innovative new technology has led researchers to suggest RNA-chromatin interactions may play a role in gene regulation.
news
Depletion and repopulation of microglia could be a future therapy for TBI
Researchers have shown that by effectively resetting the microglia, recovery of mice after a traumatic brain injury (TBI) was improved.
