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Cancer immunotherapy drug discovery outsourcing size to increase globally
A report has shown that the immuno-oncology drug discovery outsourcing market is set to be worth $2563 million by 2030.
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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T-cell redirecting bispecific antibodies: the next era of immune-based therapies for multiple myeloma?
While the introduction of novel immunotherapies to combat and treat cancer has advanced patient care greatly, ever more effective solutions continue to be required. Here, Dr Edmond Chan, Senior Director, EMEA Therapeutic Area Lead, Haemato-Oncology at Janssen Europe, Middle East & Africa (EMEA), explores how T-cell redirecting bispecific antibodies (TRBAs)…
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Monoclonal antibodies as a strategy to fight cancer
In this exclusive Q&A, Dr Veysel Kayser, Associate Professor at the University of Sydney, Australia, outlines why monoclonal antibodies (mAbs) are such an important tool to combat cancer. He also relates his recent research, as well as the latest trends in the industry.
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Novel method could determine which lymphoma patients will respond to CAR T-cell therapy
A new high-throughput approach has shown how patients whose tumours express CD58 are more likely to respond to CAR T-cell therapy.
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Cellular ‘waste product’ could enhance cancer immunotherapy, study shows
A new study has shown that lactate, a metabolic byproduct produced during exercise, could augment current cancer immunotherapies.
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Findings on pancreatic cancer could improve immunotherapies
Researchers have revealed the immune landscape and microbiome of pancreatic cysts as they progress to pancreatic cancer, providing targets for immunotherapy.
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Researchers find CD39 inhibition could be an effective strategy for immunotherapy
Scientists have discovered adenosine could inhibit CD39, a molecule that suppresses the immune system.
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New method by which T cells can react to lower doses of antigens
Researchers have discovered a way to ignite T cells, potentially increasing the scope and success of T cell-based immunotherapy.
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How T cells migrate from the tissue to the lymph nodes
Scientists have found that unconventional T cells migrate from tissue into the lymph nodes and influence immune responses there.
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A modified TB vaccine could treat bladder cancer
An animal study has shown that a modified vaccine for tuberculosis could treat bladder cancer whilst minimising side effects.
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New research finds cancer-associated fibroblasts can promote or inhibit drug sensitivity
Researchers found that fibroblasts had varying effects on tumour cells based on both the type of non-small cell lung cancer and the drug used for treatment.
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Targeted cancer vaccines eliminate tumours and prevent recurrence in mice
Researchers have developed an mRNA-based cancer vaccine that is delivered directly into the lymphatic system for a more potent response.
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Scientists have identified novel molecular biomarkers in cells that spread triple-negative breast cancer
The researchers identified key molecular differences between triple-negative breast cancer cells that cling to an initial tumour and those that venture off to form distant tumours.
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A new study has highlighted how an antibody strengthens bonds between cells
The monoclonal antibody 19A11 binds E-cadherin, a protein that helps cells stick together, especially in epithelial layers that line the skin, the gut and other organs.
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Scientists uncover new therapeutic target for treating colorectal tumours
New study has demonstrated that mice deficient in dendritic cell immunoreceptor are resilient against colitis and colonic tumour growth.
