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Protein inhibitor could be new treatment for liver cancer
US scientists have found strong evidence for testing VCU-manufactured drugs in liver cancer.
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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Metastatic potential of cancer cells increased in high viscosity environments
UPF and John Hopkins scientists have discovered how cancer cells exposed to high viscosity environments change their movements to improve their invasiveness and favour metastases.
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Cancer therapy shows potential to treat severe COVID-19 patients
Pre-clinical experiments involving cells from ICUs patients infected by SARS-CoV-2, and mice infected by MHV-A59 (murine hepatitis virus A59) show promise in treating COVID-19.
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Targeting of immune cells slows cancer growth in pre-clinical studies
Researchers have discovered a new cancer immunotherapy approach that shrinks solid tumours.
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Implant in mice most effective treatment for pancreatic cancer yet
A new implant that combines internal radiation and chemotherapy dissolved tumours in mice across multiple models.
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Discovery of two drugs could lead to earlier pancreatic cancer treatment
In pre-clinical studies, the University of Florida has identified two drugs that reverse ADM, a process that precedes pancreatic cancer.
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A new mechanism of drug resistance discovered for breast cancer
The scientists found the mechanism of drug resistance depends on activation of a protein called KDM1B which controls and regulates gene expression.
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Study uncovers relationship between T cells and CD4
Researchers at the University of Arizona Health Sciences found that CD4 plays an active role in regulating T-cell receptor signalling.
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New gene target for small-cell lung cancer discovered
Deleting the gene POU2AF2 kills cancer cells in deadly subtype of small-cell lung cancer.
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Scientists inhibit cancer cell growth using pyrrolizidine alkaloid
Researchers in Japan have succeeded in inhibiting cancer cell growth using pyrrolizidine alkaloid, a component of plant origin previously thought to be too toxic to administer.
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Cancer immunotherapy drug discovery outsourcing size to increase globally
A report has shown that the immuno-oncology drug discovery outsourcing market is set to be worth $2563 million by 2030.
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T-cell redirecting bispecific antibodies: the next era of immune-based therapies for multiple myeloma?
While the introduction of novel immunotherapies to combat and treat cancer has advanced patient care greatly, ever more effective solutions continue to be required. Here, Dr Edmond Chan, Senior Director, EMEA Therapeutic Area Lead, Haemato-Oncology at Janssen Europe, Middle East & Africa (EMEA), explores how T-cell redirecting bispecific antibodies (TRBAs)…
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Monoclonal antibodies as a strategy to fight cancer
In this exclusive Q&A, Dr Veysel Kayser, Associate Professor at the University of Sydney, Australia, outlines why monoclonal antibodies (mAbs) are such an important tool to combat cancer. He also relates his recent research, as well as the latest trends in the industry.
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Novel method could determine which lymphoma patients will respond to CAR T-cell therapy
A new high-throughput approach has shown how patients whose tumours express CD58 are more likely to respond to CAR T-cell therapy.
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Cellular ‘waste product’ could enhance cancer immunotherapy, study shows
A new study has shown that lactate, a metabolic byproduct produced during exercise, could augment current cancer immunotherapies.
