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Alzheimer’s disease linked to tau-mediated RNA splicing errors
A new study has shown the possibility of using RNA splicing as a potential molecular target for Alzheimer's disease.
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Gene therapy for DMD safely preserves muscle function
Gene therapy for the treatment of Duchenne muscular dystrophy has safely stopped the muscle deterioration associated with the disease.
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New technology invented to streamline drug discovery
New protein-painting technology could lead to developing cancer immunotherapy medicines that can be administered as a pill.
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New compound keeps cells alive and functioning in a healthy state
A world-first compound that can keep cells alive and functioning in a healthy state could be revolutionary for medical emergencies.
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Antibodies used to treat and reverse MS symptoms in mice
Researchers have identified a protein on the surface of cells that cause MS and have used antibodies as an effective treatment for the condition in mice.
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Protein receptor linked to cell death imaged for the first time
Researchers have imaged an inflammation-related protein receptor on cell membranes which could inform future drug designs to prevent cell death.
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Potential treatment for heart attacks discovered by researchers
Researchers have uncovered a treatment that may be used to treat heart attacks or to prevent heart failure, using the circadian clock.
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Researchers discover new pathway to treat Ewing sarcoma
A study has demonstrated that blocking certain receptors in mice reduced Ewing sarcoma growth and metastasis, which could be used within future treatments.
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Protein responsible for muscle degeneration identified
A study has demonstrated that a certain protein is critical in the decline of muscle regeneration, with the researchers also showing how to inhibit this process in mice.
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Scientists discover unique imaging technique to view synapse proteins
Researchers in the US have devised a new way to clearly image proteins located in synapses, which they hope will faciliate future treatment for diseases associated with blocked gene expression.
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Novel CAR T-cell therapy for leukaemia and lymphoma
Scientists in the US have developed a promising new CAR T-cell therapy that targets the BAFF-R protein, which has demonstrated superior cancer destruction to existing FDA-approved CAR-T therapies.
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Key protein in chikungunya virus replication identified
Researchers have found that the FHL1 protein plays a key role in chikungunya virus replication and pathogenesis.
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Method to reactivate ‘tumour suppressor’ genes discovered
A new method to reactivate 'tumour suppressor' genes switched off by cancer cells could lead to new targeted biotherapies for cancer.
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New study shows insight into how cells maintain their identity
A new study shows the ways in which epigenetic mechanisms control the activity of genes and may have an impact on the future treatment of certain cancers.
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Dysfunctional insulin release mechanism identified
A mechanism has been identified which regulates the release of insulin from β-cells and could be used to develop new treatments for type 2 diabetes.
