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High doses of favipiravir combat SARS-CoV-2 in hamsters
A team showed that high doses of favipiravir can treat hamsters infected with SARS-CoV-2, whereas hydroxychloroquine has no effect.
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Research & Development
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Researchers suggest blocking factor D protein could combat SARS-CoV-2
A team has said that inhibiting the factor D protein could prevent SARS-CoV-2 from turning the immune system against healthy cells.
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New class of inhibitors protect mice from neurodegeneration
So called "interface inhibitors" could be used to protect against neurodegeneration, researchers have said.
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SARS-CoV-2 mechanism of infection revealed using cryo-electron microscopy
Researchers have found that the surface of SARS-CoV-2 can take on at least 10 different structural states when in contact with ACE2.
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Researchers make steps towards a universal flu vaccine
A research team has developed a potentially universal flu vaccine that has demonstrated success in mice.
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NIH to support 85 highly innovative research projects
The US National Institutes of Health (NIH) will award a total of $251 million over five years to 85 high-risk, high-reward biomedical or behavioural research projects.
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Lead drug candidate identified as potential neuroblastoma treatment
Using hit-to-lead processes, researchers have discovered that KSP inhibitors prevent tumour growth and prolong survival in mice with neuroblastoma.
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2020 Nobel Prize goes to discoverers of hepatitis C
The 2020 Nobel Prize in Physiology or Medicine has been bestowed upon researchers who helped identify the hepatitis C virus in the 1970s.
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Gramicidin A antibiotic analogues safe for human cells developed
A team has developed 10 new versions of the antibiotic gramicidin A, which they say should be safe for use in pills or injections.
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Platform for hit-to-lead identification of antibacterial lysins developed
A group of scientists has created a novel high-throughput hit-to-lead development platform to identify engineered antibacterial lysins.
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Two cytokines found to cure and prevent rotavirus infection in mice
Researchers have found that the cytokines IL-18 and IL-22 can combat and cure rotavirus infections in mice.
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SARS antiviral nitric oxide could be used to treat SARS-CoV-2
The nitric oxide treatment used during the 2003 SARS epidemic could be used as an antiviral against SARS-CoV-2, researchers say.
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Hit-to-lead from small molecule library screens can identify new vaccine adjuvants
Researchers have screened small molecule libraries and then applied hit-to-lead approaches to discover effective vaccine adjuvants.
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Team identifies T-cell epitopes to inform COVID-19 vaccine development
Researchers studied 180 convalescent COVID-19 patients to reveal T-cell epitopes that they say can be targeted by a vaccine.
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Malaria compounds found to kill Cryptosporidium parasite
Researchers have shown that bicyclic azetidines, medicines used to treat malaria, can also kill the Cryptosporidium parasite in mice.
