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ebook: Accelerating antibody discovery
Hybridoma-based antibody discovery: the challenges and how to overcome them using microfluidic picodroplet technology.
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New variant of the GLA gene to be linked with Fabry cardiomyopathy
A study in Finland has found a strong connection between the A143T variant of the GLA gene and increased risk of Fabry cardiomyopathy, which affects the heart, kidneys and nervous system.
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Remdesivir demonstrates success against MERS in rhesus macaques
The experimental remdesivir drug has shown efficacy in combatting the MERS virus in rhesus macaques, according to a new US study.
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YAP protein identified as new target for Alzheimer’s disease
Researchers have discovered that neuronal necrosis occurs in Alzheimer's earlier than previously though and revealed the YAP protein as a potential target.
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Application note: Evaluation of hepatic function in 3D culture
In vitro evaluation of hepatic function using a primary human hepatocyte 3D spheroid culture system
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Application note: Hypoxia measurements in live and fixed cells
Hypoxia measurements in live and fixed cells using fluorescence microscopy and high-content imaging
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Innate protein restricts HIV replication by targeting lipid rafts
According to a new study, apolipoprotein A-I binding protein restricts HIV-1 replication by targeting lipid rafts and reducing virus-cell fusion.
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The fate of cancer is all down to particular proteins
Scientists in Japan have identified an important protein that can impact the course of cancer and its fate in the human body.
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Molecular ‘switch’ could help treat or reverse age-related diseases
A molecular 'switch' that controls the immune machinery responsible for chronic inflammation has been identified which could help treat or even reverse the development of age-related conditions like Alzheimer's, Parkinson's, cancer and diabetes.
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Blocking IL-17 could provide new multiple sclerosis treatment strategy
Researchers have revealed that inhibiting IL-17 could prevent the effects of autoimmune diseases, including multiple sclerosis.
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Application note: Low volume, high-throughput subvisible AAV aggregate analysis with Horizon
Are you missing the bigger picture with your AAV analytics? Subvisible particle analysis should not require millilitres of precious sample.
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Imaging technique reveals how HIV drugs bind to viral structure
A new study has shown in three dimensions how drugs bind to HIV, which could be used to improve the design of drugs or develop novel therapies.
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Novel antiviral material made from sugar developed by researchers
Modified sugar molecules have been developed by researchers as antiviral materials which are non-toxic to humans, according to a new study.
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Missing link found in rare inherited skin disease
Scientists are getting closer to understanding how a rare hereditary disease impairs the skin's barrier function, which determines how well the skin is protected.
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Autophagy: the key to effective MERS-coronavirus treatment?
A promising route for tackling the often-fatal MERS-coronavirus (MERS-CoV) has been identified by researchers in Germany.
