Application note: 3D image analysis and characterisation of angiogenesis in organ-on-a-chip model

Posted: 22 September 2020 | | No comments yet

Many anti-angiogenic drugs have been developed to use in cancer therapy, while pro-angiogenic molecules may hold potential in regenerative applications.

This new application note from Molecular Devices, in collaboration with MIMETAS, describes imaging and analysis methods for obtaining multiple quantitative descriptors of angiogenesis that could be used for comparative research into disease phenotypes and compound effects

• Visualise angiogenic sprouting and 3D reconstitution of structures
• Perform quantitative assessment of angiogenesis, including number of sprouts, total volume, and average intensity
• Generate physiologically-relevant results using the OrganoPlate® platform