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Specific mechanism found to control transition from acute to chronic pain
A new study is the first to identify N-acylethanolamine acid amidase as a new drug target to treat different forms of chronic pain.
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Chronic pain
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Peptides: a promising alternative to opioids for chronic pain relief
In an exclusive with Drug Target Review, researchers at the University at Buffalo explain how they developed a novel peptide that could be a future treatment for chronic inflammatory pain.
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Nobel Prize for medicine awarded to temperature and touch discoveries
David Julius and Ardem Patapoutian have won the 2021 Nobel Prize for Physiology or Medicine, with their work being used to develop treatments for conditions such as chronic pain.
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Millennia in the making: unlocking the medicinal value of CBD
Dr Sotirios Karathanasis discusses the history of cannabis as a treatment and delves into the process of turning plant-based medicines into clinically proven drugs.
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CRISPR-dead Cas9 could offer non-addictive treatment for pain, study shows
A new CRISPR gene therapy for chronic pain has been shown in mice to temporarily repress a gene involved in sensing pain.
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Novel class of non-addictive analgesics demonstrate safety in animals
To overcome the issues of current analgesics, researchers reveal a new class of non-narcotic pipeline drugs based on acetaminophen.
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Effective analgesics are ‘some way away’ due to bias in pain research, says researcher
A review of pain research suggests it is biased towards males, despite most chronic pain sufferers being female, resulting in ineffective analgesics.
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Neuronal link between chronic pain and depression discovered
The mechanism in the brain connecting chronic pain and depression could lead to treatments for both, according to researchers.
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New target for chronic pain relief
Scientists observe drug target that can reduce pain when activated...
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Developing a blood test for pain measurement
A blood test to measure pain has been developed, and could potentially aid physicians with more accuracy in diagnosis and prescriptions...
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Perrottetinene from moss could be more medically beneficial than hemp
Researchers have found that moss could be more medically beneficial than tetrahydrocannabinol (THC) which is being used illegally to treat various diseases...
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A new generation of pain relief
Researchers have developed a new generation of pain relief drugs that only target the affected area, with the help of computer simulations...
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Scientists discover compound for a non-addictive painkiller
Scientists have discovered the chemical compound AT-121, which could soon lead to a painkiller stronger than morphine, but without the side effects...
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How cannabis and cannabis-based drugs can harm your brain
Long-term use of either cannabis or cannabis-based drugs impairs memory...
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Derm-BOT compound relieves chronic pain
A modified form of botulinum toxin gives long-lasting pain relief in mice without adverse effects...