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Anti-linker antibodies: a universal key for CAR-T detection
Every new CAR-T needs a new detection tool – until now. Anti-linker antibodies could change how researchers develop and track these therapies.
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Multiple Sclerosis
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Reducing sclerosis inflammation in mice
Researchers have been able to reduce the chronic inflammation associated with multiple sclerosis in a mice model of the disease, by administering one of the resolving lipid mediators of inflammation, Maresin-1.
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Virtual method enables screening of billions of chemical compounds
A new platform, named Virtual Synthon Hierarchical Enumeration Screening, has been developed by researchers to efficiently discover drugs.
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New Oxford-GSK Institute aims to unravel complex diseases
GlaxoSmithKline (GSK) and the University of Oxford will collaborate to investigate diseases using technologies such as functional genomics and machine learning.
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CRISPR screen unveils enzyme target for inflammatory diseases
Scientists used a CRISPR-based screen to find that inhibiting MTHFD2 reduces disease severity in inflammatory disease models.
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Novel form of cell-free therapy revealed by researchers
Researchers have developed cytochalasin B-induced membrane vesicles which they suggest could be a new form of cell-free therapy in regenerative medicine.
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Protein vital for T cell formation and function revealed
Researchers have discovered a protein that is required for T cell biological processes; they have also demonstrated the mechanism behind the protein.
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Protein receptor linked to cell death imaged for the first time
Researchers have imaged an inflammation-related protein receptor on cell membranes which could inform future drug designs to prevent cell death.
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MS treatment potential after condition-causing genes identified
Researchers have found 12 genes which cause MS, creating potential for preventative treatment of the condition.
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New therapeutic concept controls pathogenic T-cells relevant in MS
Researchers have identified an innovative and promising therapeutic option to treat multiple sclerosis...
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Inflammation inhibitor could be used to treat sepsis
An inhibitor that stops the action of OGG1 signals, could potentially be used as a treatment for life-threatening Acute Respiratory Distress Syndrome...
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Lymphatic brain vessels represent potential avenue for MS treatment
Researchers in the U.S. have identified that lymphatic vessels in the brain appear to play a crucial role in the development and progression of multiple sclerosis (MS), providing focus for new treatment research.
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How cannabis and cannabis-based drugs can harm your brain
Long-term use of either cannabis or cannabis-based drugs impairs memory...
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P2X4 receptor key for delaying the progression of Multiple Sclerosis
Researchers have identified a receptor in the microglial cells that increases their anti-inflammatory potential in order to reduce the damage in MS...
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Scientists uncover the role of PRMT5 in the production of myelin-forming cells
The discovery is a major step toward understanding the mechanisms of myelin production and the potential for treating certain central nervous system diseases...
