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Pancreatic cancer

DTR’s news round-up 2019: the stories that defined the year

18 December 2019 | By Drug Target Review

Drug Target Review lists its 10 most popular news stories from 2019, summarising the drug targets that you wanted to read about.

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Mechanism revealed which help pancreatic cancer cells avert starvation

17 December 2019 | By Rachael Harper (Drug Target Review)

A mechanism has been revealed that could be used to deny RAS mutant tumour cells (which is known to encourage the growth seen in pancreatic cancer patients) of a key survival mechanism.

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Five recent drug target discoveries for pancreatic cancer

11 December 2019 | By Hannah Balfour (Drug Target Review)

This article highlights some of the most recent drug target discoveries that could be used to develop and design a treatment for pancreatic cancer.

cartoon pancreas with red 'tumour' highlighted

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PJ34 triggers self-destruction of human pancreatic cancer cells

3 December 2019 | By Hannah Balfour (Drug Target Review)

A study conducted on human pancreatic tumours transplanted in mice reveals promise for an effective therapy in the future, say researchers.

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Researchers develop vaccine with potential to treat pancreatic cancer

27 November 2019 | By Victoria Rees (Drug Target Review)

A study has demonstrated that a novel vaccine design for pancreatic cancer has been successful in mice, doubling survival time.

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Silencing RNA nanotherapy shows promise in treating pancreatic cancer

22 October 2019 | By Rachael Harper (Drug Target Review)

Peptide-based nanoparticles have been designed which can suppress pancreatic cancer growth without the toxic side effects.

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Cancer-suppressing cells identified in pancreatic cancer

14 October 2019 | By Rachael Harper (Drug Target Review)

Cells containing Meflin play a role in restraining the progression of pancreatic cancer and could lead to new therapies against the disease.

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Study reveals how to make pancreatic cancer chemotherapy more effective

19 September 2019 | By Victoria Rees (Drug Target Review)

Researchers have shown that blocking a particular enzyme causes chemotherapy to become more effective against pancreatic cancers in pre-clinical studies.

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Overcoming resistance in pancreatic cancer treatment

10 September 2019 | By Rachael Harper (Drug Target Review)

Researchers have developed a new cocktail of drugs that shrink pancreatic tumours in mice by blocking pathways that cancer cells use.

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Molecule identified as key in pancreatic cancer metastasis

12 August 2019 | By Victoria Rees (Drug Target Review)

New findings show that the environment for pancreatic cancers plays a role in its metastasis, revealing a new potential drug target.

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Experimental compound could be used to treat pancreatic cancer

9 August 2019 | By Victoria Rees (Drug Target Review)

Using a compound called PTC596 in combination with other drugs, researchers effectively treated pancreatic cancer in mice.

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Antibody therapy extends survival in mice with pancreatic cancer

1 August 2019 | By Rachael Harper (Drug Target Review)

Scientists have found a way to target and knock out a protein which is widely involved in pancreatic cancer cell growth, survival and invasion.

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Promising drug developed for ovarian and pancreatic cancers

22 July 2019 | By Drug Target Review

An antibody has been developed to block a protein secreted by the cells surrounding ovarian and pancreatic cancer tumours.

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Research shows pancreatitis biomarker linked to pancreatic cancer

25 June 2019 | By Victoria Rees (Drug Target Review)

A study has discovered that a biomarker associated with pancreatitis is involved in its development to pancreatic cancer.

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New nanomachines developed to deliver cancer drugs to hard-to-reach areas

29 April 2019 | By Drug Target Review

In a recent study in mice, researchers have found a way to deliver specific drugs to parts of the body that are exceptionally difficult to access.

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Pancreatic cancer