Spatial biology is the next life science revolution
Dr Richard Goodwin, Head of Imaging & AI, Clinical Pharmacology & Safety Sciences at AstraZeneca, explores the latest innovation in early therapeutic development – spatial biology.
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Dr Richard Goodwin, Head of Imaging & AI, Clinical Pharmacology & Safety Sciences at AstraZeneca, explores the latest innovation in early therapeutic development – spatial biology.
Researchers have developed a ground-breaking microscopy technique that allows proteins, DNA, and other tiny biological particles to be studied in their natural state in a completely new way.
In this section, Dr Peter O’Toole, University of York, examines innovation in the field of microscopy for drug discovery and development research, while in an exclusive Q&A, Dr Michael Grange, Rosalind Franklin Institute, discusses the advantages of utilising cryo-electron tomography imaging.
In this issue are articles focusing on a novel stem cell therapy for hearing loss, how a non-linear chiroptical effect could aid drug discovery and the advantages of cryo-electron tomography for imaging research. Also included are pieces on gene therapy, spheroids and genomics.
This guide shows how to reduce cost and time by setting up reproducible HTS/HCS with 3D cell culture models with animal-free GrowDex® hydrogels.
Ultra-powerful 7T MRI scanners could be used to help identify those patients with Parkinson’s disease and similar conditions most likely to benefit from new treatments for previously untreatable symptoms.
New data from high-resolution imaging has revealed the origin of circulatory system during development, a discovery that could help advance therapeutics for various vasculature-related pathologies.
In this episode, experts explore the benefits of 3D imaging and the important considerations for organoid workflows in research and drug development.
The ImageXpress Confocal HT.ai High-Content Imaging System combines premium hardware technology with a self-learning software analysis workflow for increased signal and ultra-fast 3D organoid screening.
Columbia-led team wins research grant to create fundamentally new maps that will chart cell diversity throughout the brains of humans.
Read this bulletin to learn about a Bio-Rad study where they developed and tested a 16-parameter flow cytometry panel applicable to the interrogation of a range of biologically relevant markers of T cell activation.
Improving processes in the lab can enable researchers to spend their time on other tasks and increase the accuracy of their findings, including when imaging. In this Q&A, Dr Hari Shroff from the US National Institutes of Health (NIH) discusses his recent study, published in Nature where confocal microscopy was…
In this issue are articles on the development of mRNA vaccines against latent viruses, how memory B cell antibody-based treatments can help to fight cancer and the potential of AI in drug discovery. Also included are pieces on biotherapeutics, immuno-oncology and assays.
Researchers have developed a new imaging approach that can capture blood vessel images at different spatial scales.
Scientists have demonstrated how automated, high-throughput life science experiments can be replicated on a modest budget.