news
Novel anti-inflammatory slows progression of MS in mice
When delivered intranasally, the anti-inflammatory drug VX-765 prevented axon demyelination and loss in a murine model of multiple sclerosis (MS).
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Imaging
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Webinar: High-content analysis and phenotypic characterisation of 2D and 3D cellular models
Combining 2D and 3D models with live-cell assays allows monitoring of cell responses in real time and provides important insights about compound treatment effects, biological complexity, and physiological relevance of assay results.
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Application note: Phenotypic characterisation of neuroactive compound effects
Learn how to perform complex analysis of calcium oscillations and assess cellular and mitochondrial toxicity.
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Whitepaper: The impact of COVID-19 on neurological systems
Neurological symptoms have been observed in COVID-19 patients. The link between SARS-CoV-2 and the CNS is critical to developing effective treatments
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Video: Gain deeper insights into cellular 3D structures with water immersion objectives
Water immersion objectives are essential for capturing more data at greater depths in 3D structures, such as spheroids and thick tissues.
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Application note: Assess transduction efficiency of CFP-tagged nuclear protein with automated cellular imaging
Evaluating and quantitating nuclear transduction.
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SARS-CoV-2 mechanism of infection revealed using cryo-electron microscopy
Researchers have found that the surface of SARS-CoV-2 can take on at least 10 different structural states when in contact with ACE2.
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Application note: Monitor mitochondria dynamics and phenotype with high-content imaging
There has been growing interest in using high-content imaging methods for studying mitochondria.
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Video: ImageXpress Pico Virtual Tour
Explore this virtual tour of the ImageXpress Pico Automated Cell Imaging System from Molecular Devices, including hardware and software.
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Interactive 3D model of SARS-CoV-2 surface released
A new interactive map of the surface of SARS-CoV-2, featuring the Spike, Envelope and Membrane proteins, has been released for researchers to use.
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Video: ImageXpress Micro Confocal Virtual Tour
Explore this virtual tour of the ImageXpress Micro Confocal High-Content Imaging System from Molecular Devices, including hardware and software.
webinar
Next generation strategies for cancer immunotherapy
24 September 2020 | By PerkinElmer
During this on-demand webinar, two leading researchers will discuss their innovative approaches to developing novel opportunities for immunotherapy treatments.
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Webinar: Optimised workflow for rapid identification of neutralising antibodies against viral particles
Helping in the race to identify effective neutralising antibodies against the spike protein of SARS-CoV-2 virus as the COVID-19 global death rate continues to rise.
news
Researchers discover druggable pocket on SARS-CoV-2 Spike protein
A pocket in the SARS-CoV-2 Spike protein has been discovered by researchers, who say it could be a drug target for COVID-19.
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Application note: 3D image analysis and characterisation of angiogenesis in organ-on-a-chip model
Many anti-angiogenic drugs have been developed to use in cancer therapy, while pro-angiogenic molecules may hold potential in regenerative applications.
