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Parkinson’s disease symptoms “improved” by oestrogen
New research into sex-based differences of Parkinson's disease could lead to new treatments.
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Direct toxic action of beta-amyloid in Alzheimer’s patients identified
The cause and trigger of the large clumps of protein beta-amyloid found in the brains of early-stage Alzheimer's patients have been discovered.
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CRISPR-Cas used to edit cystic fibrosis gene mutations
A research team have used genome editing to correct two of the mutations that cause cystic fibrosis.
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New model can help translate mice research into human health results
A new mouse model, called 'wildlings', has been developed which better mirrors human immune responses than standard laboratory mice.
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Targeting a blood stem cell subset shows lasting gene editing
Scientists report how editing a portion of stem cells with CRISPR-Cas9 is sufficient for long-term reactivation of therapeutic haemoglobin.
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Study of TP53 mutations shows insight into the gene’s function
New study sheds light on how the TP53 gene becomes mutated and how those mutations can help predict clinical outlooks for cancer.
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No-cut CRISPR could be used to treat muscular dystrophy
Researchers have successfully used a no-cut CRISPR gene editing technique as a therapy for muscular dystrophy in mice models.
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Study discovers key process in the cause of cell aging
Researchers have identified a key process behind senescence, or why cells age, which could be used to improve treatments for cancer.
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New system enables improved pre-clinical testing of heart drugs
Researchers have extended the life of heart segments from 24 hours to six days, enabling pre-clinical trials to experiment on these new models for longer periods of time.
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Scientists control living cells using artificial protein switch
Scientists have created the first completely artificial protein switch that can be ‘programmed’ to modify gene expression.
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Transfer of oncogene in colon cancer cells demonstrated
A new study has shown that proteins derived from the oncogene, KRAS, can transfer between colon cancer cells.
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Gene differences that impact response to Cryptococcus identified
Using human data, a new study has examined how Cryptococcus genes impact patients with Cryptococcus Neoformans.
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Novel nanoparticles improve CRISPR gene editing
A study has used new synthetic lipids to deliver CRISPR gene editing tools into cells with up to 90 percent efficiency.
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‘Longevity gene’ could be replicated to fight cardiovascular disease
The so-called 'longevity gene' has been included in animal models, in which it stopped atherosclerosis.
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Secondary structures study could lead to making cancer cells vulnerable
Researchers have used machine learning to discover that the two most widespread DNA structures cause genome mutations that lead to cancer.
