Novel palladium compound shows potent action against treatment resistant cancer cells
Research demonstrated a complex of palladium and thiosemicarbazone is a more selective and powerful chemotherapeutic than the current standard of care cisplatin.
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Alternative splicing regulators like AKAP8 prevent cancer metastasis
A study revealed that AKAP8 promotes the alternative splicing of proteins, preventing breast cancer metastasis in animal models and could be the target of future therapies.
Small molecule targeting mRNA could slow the progression of Parkinson’s disease
Research identified a small molecule that targets the mRNA of α-synuclein and prevents the formation of the protein, an approach which could provide novel neurodegeneration therapies.
Cannabinoid screening reveals anti-tumour properties of CBC and CBG
A high-throughput screening test of different cannabinoids has demonstrated that CBC and CBG exhibit anti-tumour effects.
DNA-PK identified as potential targeted therapy for cancer
A study has shown that the sensor of a DNA sensing pathway, DNA-PK, could act as an antiviral against tumours.
Tobacco mosaic virus creates novel malaria vaccine candidate
Researchers in the United States have used particles from the tobacco mosaic virus (TMV) to produce a new much-needed malaria vaccine.
Boris Johnson announces UK Global Talent visa for researchers
Boris Johnson, the Prime Minister of the UK, has announced a new Global Talent visa for researchers and scientists which will fast track those in certain fields.
PPARγ identified as liver fibrosis ‘off-switch’ in mice
A study identifying transcription factor differences in the hepatic stellate cells of mice with liver fibrosis named PPARγ as a potential target for the condition’s regression and scar resolution therapies.
Researchers use iPSCs to treat neuropathic pain in mice
Induced pluripotent stem cells (iPSCs) have been administered to mice with neuropathic pain to provide lasting relief with no side effects.
CEPI announces three programmes to develop coronavirus vaccine
The CEPI has announced three respective projects with Inovio, the University of Queensland and Moderna, to develop a vaccine for the novel coronavirus, nCoV-2019.
Cancer metastasis can be prevented by stopping lipid storage in mice
A study has demonstrated the aggressiveness of cancers is promoted by their ability to store fatty acids in lipid droplets; this discovery could lead to new anti-metastasis therapies.
Diabetes-related proteins examined for the first time at high resolution
A key receptor has been examined for the first time at high resolution which could lead to better treatments for conditions such as type 2 diabetes.
Study identifies gene responsible for T follicular helper cell development
A loss-of-function mutation in the Prkd2 gene has been revealed as a driver of T follicular helper cell development which could be useful for vaccine design.
Techniques to disrupt HIV viral latency could help a future cure
Two possible therapeutic approaches to cause dormant HIV to re-emerge from their latency reservoir could provide new possible avenues to a cure for HIV, says research.
Antiviral treatments lead to development of a new kind of cancer drug
Drugs that were being developed to treat enterovirus have also been found to treat certain cancers in mice.
