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Scientists have discovered a powerful new antibiotic hidden within the compound pre-methylenomycin C lactone, which shows real effectiveness against drug-resistant infections such as MRSA and VRE.
Protein released by C. burnetti interacts with antioxidising enzyme GPX4 to prevent cell damage and death.
Australian scientists explored a group of bacterial pathogens that share a protein sequence which is recognised by human T cells.
Researchers have discovered a way to ignite T cells, potentially increasing the scope and success of T cell-based immunotherapy.
Researchers have discovered a new pathway to the regeneration of insulin in pancreatic stem cells, findings that could move towards new therapies for type 1 and type 2 diabetes.
New research has found that microbial fermentation of dietary fibre in the gut can protect against allergic skin diseases.
Scientists have developed a metal-organic framework that, when attached to antibodies, improved their targeted delivery in in vitro studies.
A team has characterised a key part of the peptide synthesis process, showing that only the main building block needs to be changed for re-engineering.
Researchers have used cryo-EM to show that a new nanobody cocktail can bind to the S protein of SARS-CoV-2, neutralising the coronavirus.
Scientists have created the first model of early human embryos by reprogramming fibroblasts into a blastocyst-like structures.
A key process in β-cell regeneration has been discovered by researchers who say this could lead to improved treatments for diabetes.
In a zebrafish model, researchers have found that the protein NAPMT can trigger muscle stem cells to proliferate and heal muscle damage.
Researchers have discovered that giving L-tyrosine and PCS to mice prevents lung inflammation and an allergic asthma response.
![Ovarian cancer cells forming a cancer spheroid as they grow within the peptide-protein co-assembling material [Credit: Alvaro Mata].](https://www.drugtargetreview.com/wp-content/uploads/ovarian-cancer-spheroid-3D-model-750x500.jpg)
![Ovarian cancer cells forming a cancer spheroid as they grow within the peptide-protein co-assembling material [Credit: Alvaro Mata].](https://www.drugtargetreview.com/wp-content/uploads/ovarian-cancer-spheroid-3D-model-e1601896830935.jpg)
Researchers have developed a new self-assembling three-dimensional (3D) ovarian cancer tumour model to recreate the in vitro disease more accurately.
A novel drug has been created which prevented the blood clotting associated with heart attacks and strokes in pre-clinical studies.
