Scientists have discovered adenosine could inhibit CD39, a molecule that suppresses the immune system.
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University of Bonn
The new group of molecules can be chemically altered, showing potential for the development of effective antibiotics with few side effects.
Scientists have identified a subpopulation of mesenchymal stem cells with enhanced bone fracture healing and differentiation abilities.
An aptamer that can bind a different part of SARS-CoV-2 than known inhibitors could enhance treatments against coronavirus mutations.
Using high-throughput screening techniques, researchers have identified two families of active substances that block SARS-CoV-2 replication.
By combining nanobodies targeting different regions of the SARS-CoV-2 Spike protein, researchers were able to protect cells from infection.
Researchers have found a way to systematically extract various cell types from induced pluripotent stem cells and made their transcription factor source accessible for other scientists.
Researchers have found that the structure of biocatalysts such as enzymes depends on whether they are in cells or in the test tube.
Researchers have optimised PROTAC substances to degrade and dispose of proteins that support cancers, by customising their structure and selecting the best ligases.
A study has found the processes used by macrophages in their immune response, which could be used in the development of new vaccines.
Researchers have presented a systematic catalogue of specific variable locations in the genome that influence gene activity in the human hippocampus...
The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is establishing 15 new Research Training Groups to further support early research...
Dendritic cells are gatekeepers of immunity and crucial for the detection and initiation of immunity against pathogens and foreign substances. Up to now, dendritic cell subtypes were thought to develop from one common progenitor. New findings from a team of researchers show with single cell resolution that this important component…
Epilepsy is a complex neurological disorder that afflicts approximately 50 million people worldwide. Although this disease has been known to exist for centuries, the exact mechanism of its cardinal symptom, the epileptic seizure, remains poorly understood. In fact, roughly 25% of epileptic seizures can’t be controlled by any of the…