In Alzheimer’s disease patients, irritability and anxiety is likely caused by neuroinflammation, which indicates new therapeutic pathways.
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University of Pittsburgh School of Medicine
Researchers from UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of Medicine have made a discovery linking the notorious cancer-causing gene, Myc, to the process of ageing.
Using flow cytometry, Dr Greg Delgoffe and Dr Paolo Vignali highlight that low oxygen environment of tumours can prompt exhausted T cells to suppress the immune system instead of combating cancer.
A new study has provided insights into how a novel tuberculosis vaccine strategy could work by speeding up the T cell responses in the lungs to shut down infection rapidly.
Researchers have shown that inhalable nanobodies at ultra-low doses can effectively neutralise SARS-CoV-2 in hamsters.
Three separate studies have identified nanobodies – a miniature form of antibodies found in camelid species – that can bind to the SARS-CoV-2 Spike (S) protein and neutralise the virus in cells.
Researchers reveal drugs inhibiting Neuropilin-1 (NRP1), a protein expressed on T cells, could improve the efficacy of immunotherapies.
Using new technology researchers have shown that sick mitochondria pollute the cells they are supposed to be supplying with power.
The first genetically modified mini human livers have been grown in a laboratory, to emulate liver disease progression and test therapeutics.
Genomics could be used to match drugs to patients better, with these genetic signatures also giving an earlier insight into detection of the condition...
Researchers have showed how a common virus hijacks a host cell’s protein to help assemble new viruses before they are released.
Research shows that preventing or reversing ‘T-cell exhaustion’ with targeted therapies could enhance the effects of immunotherapy.
An antibody treatment has been found to reduce the rate of flare-ups by nearly 20 percent in patients with a subgroup of treatment-resistant COPD...