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Antibodies

Chimeric Antigen Receptor T cells in red attacking cancer cells in blue

news

Experimental CAR T therapy targets solid tumour cancer cells

3 July 2020 | By Hannah Balfour (Drug Target Review)

Scientists have developed a novel chimeric antigen receptor (CAR) T-cell therapy to target a variety of human and murine solid-tumour cancer cells.

news

Researchers reveal how a key human anti-HIV antibody prevents infection

2 July 2020 | By Hannah Balfour (Drug Target Review)

The team used cryogenic electron microscopy (cryo-EM) to show how the 10E8 antibody interacts with the HIV’s fusion protein to neutralise the virus.

webinar

Drug repurposing approaches to fast track development of new therapies for COVID-19

26 June 2020 | By Tecan

This webinar described the recent efforts to identify small molecule therapeutics for the treatment of SARS-CoV-2 infection and COVID-19 disease.

whitepaper

ebook: The researcher’s guide to measuring binding affinity

24 June 2020 | By NanoTemper Technologies

Learn why measuring binding affinity is key to helping you decide the next steps in your research and what technologies are available to measure it.

news

N terminal domain of S protein revealed as antibody target for COVID-19

23 June 2020 | By Victoria Rees (Drug Target Review)

An antibody with high neutralising potency against SARS-CoV-2 that binds to the N terminal domain of the Spike protein has been identified by a team researching COVID-19 therapeutics.

whitepaper

Article: Immuno-oncology: Pushing the frontier of discovery through advanced high throughput flow cytometry

22 June 2020 | By IntelliCyt Corporation

Immuno-oncology (IO) is increasingly prized as an effective therapy in cancer management.

news

Screening reveals nelfinavir and amodiaquine combat COVID-19 in cell cultures

18 June 2020 | By Victoria Rees (Drug Target Review)

Researchers who screened 136 broad-spectrum antivirals identified six with the most activity against COVID-19 and an optimum combination of two to fight the virus.

news

New antibody cocktail developed as potential therapy for COVID-19

17 June 2020 | By Victoria Rees (Drug Target Review)

Researchers have proposed a cocktail of two antibodies which they say could provide an effective therapy for COVID-19 patients.

antibodies attacking black covid-19 particles

news

“Potent” antibodies provide protection from COVID-19 in cell cultures, finds study

16 June 2020 | By Victoria Rees (Drug Target Review)

Newly discovered antibodies found in the blood of recovered COVID-19 patients could provide robust protection against SARS-CoV-2, say researchers.

whitepaper

ebook: The definitive guide to understanding protein stability

16 June 2020 | By NanoTemper Technologies

Learn how to measure protein stability, why it’s important, and what the key technologies are available to measure it.

video

Video: ESHG 2019 conference discussion panel: automated sample preparation

10 June 2020 | By Thermo Fisher Scientfic

A result is only as good as the sample preparation that preceded it.

video

Video: Overview of the KingFisher^TM instruments

10 June 2020 | By Thermo Fisher Scientific

ESHG 2019: Automated sample preparation using magnetic bead technology and KingFisher instruments.

whitepaper

Application note: High-throughput pathogen detection using a novel MagMAX kit and OpenArray technology

9 June 2020 | By Thermo Fisher Scientfic

Automated detection and isolation of pathogens for multiple samples types.

video

Video: Isolate Circulating tumor cells using the KingFisher

9 June 2020 | By Thermo Fisher Scientfic

New opportunities for liquid biopsy: At automated workflow for isolating circulating tumor cells using KingFisher instruments.

news

Investigational anti-SARS-CoV-2 molecules show efficacy in pre-clinical studies

8 June 2020 | By Hannah Balfour (Drug Target Review)

Pre-clinical testing of the COVIDTRAP™ (STI-4398) protein and STI-1499 antibody reveal they can inhibit SARS-CoV-2 from infecting cells.

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Antibodies