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New findings could lead to a vaccine that can offer protection against emerging COVID-19 variants
Scientists have discovered antibodies that are effective against many different COVID-19 variants.
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Antibody Discovery
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A new study has highlighted how an antibody strengthens bonds between cells
The monoclonal antibody 19A11 binds E-cadherin, a protein that helps cells stick together, especially in epithelial layers that line the skin, the gut and other organs.
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Llama nanobodies could prevent a deadly post-transplantation infection
A new study has shown that nanobodies derived from llamas could have the potential to destroy human cytomegalovirus.
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An EGFRvIII-targeted immune-based therapy could potentially treat glioblastoma
A T-cell bispecific antibody shows potent anti-tumour activity in preclinical models of epidermal growth factor receptor variant III (EGFRvIII) mutant glioblastoma.
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Research reveals how maternal antibodies can protect babies from cytomegalovirus
Scientists have found antibodies that summon virus-engulfing white blood cells may play an important role in protecting infants from cytomegalovirus.
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Scientists discover an antibody that potentially acts as a therapy against SARS-CoV-2
The scientists found that the neutralising monoclonal antibody protected against SARS-CoV-2 infections in animal experiments.
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A new study sheds light onto maternal autoantibody linked to autism
The researchers found predictive protein patterns and links of maternal autoantibody–related autism spectrum disorder in the blood of expecting mothers.
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How to select the best combination of antibodies to treat HIV
A new computer-based approach could help clinicians select the best combinations of broadly neutralising antibodies to treat HIV based on the virus’ genetics, while minimising the risk of the virus escaping treatment.
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Broadly neutralising antibody protects Syrian hamsters against Omicron variants
Researchers have found that a broadly neutralising antibody displays strong antiviral activities against Omicron BA.1, BA1.1 and BA.2.
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Chicken eggs used to produce SARS-CoV-2 antibodies
Researchers in the US have found that antibodies to the SARS-CoV-2 Spike protein can be produced in hen eggs.
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Scientists capture first images of an autoantibody attacking a neuron receptor
Researchers for the first time have captured images of an autoantibody bound to a nerve cell surface receptor, revealing the physical mechanism behind a neurological autoimmune disease.
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New insight into the key properties of an antibody needed to fight cancer
The findings have enabled researchers to design antibodies to activate important receptors on immune cells and deliver more powerful anti-cancer effects.
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Novel combination therapy could eliminate colon tumours
Researchers have found that a combination therapy that incorporates a plant virus with an immune cell-activating antibody clears colon cancer in mice.
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Antibody pipelines – the pharma perspective
Dr Erik Vernet, Director of Antibody Technology at Novo Nordisk, discusses antibody discovery and development workflows, including the role of informatics processes, in this Q&A.
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Broadly neutralising antibodies could provide immunity against COVID-19 variants
A new study has highlighted two broadly neutralising antibodies show great promise to provide long-acting immunity against COVID-19 in immunocompromised populations.