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Artificial enzyme catalytic capabilities improved, say researchers
A study has shown that using a particular three-stranded structure can extend the catalytic performance of artificial metalloenzymes.
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Bioengineering
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Novel cell reprogramming cocktail could advance regenerative medicine
Scientists have showed that a three inhibitors (3i) cocktail could reprogramme fibroblasts to a naïve embryonic stem cell-like state and remove disease-associated epigenetic changes.
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Self-assembling biomaterial could be used to model vascular structures
Scientists have shown an innovative new biomaterial made of graphene oxide and proteins could be used to 3D print model vascular structures.
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Why invest in creating a modifiable drug framework?
Drug Target Review spoke with CUE Biopharma’s President and CSO to find out how and why they created the ImmunoSTAT platform and the ways it may benefit drug design in the future.
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The growing possibilities for stem cells in pharma
Drug Target Review explores the latest applications of stem cells in modelling disease, drug production and the most recent steps in regenerative medicine provided by research.
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Antibodies could be used as nanotechnology builders
Endogenous human antibodies can be used to build and dismantle 2D and 3D DNA nanostructures, finds new research.
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Method to coax immune system into selecting HIV antibodies developed
Immunogens can be used to coax the immune system into producing broadly neutralising antibodies to fight a HIV infection, making a vaccine against the condition more likely, say researchers.
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New generation of CAR T cells developed
Researchers have reprogrammed CAR T cells to prevent them becoming exhausted after prolonged activity, presenting a possible new therapy for solid tumours.
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Protein therapeutic development could be accelerated with new method
Scientists have developed a new method that accelerates the design and engineering of potential medicines and vaccines using glycosylation.
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Advanced biomaterial improves stem cell therapy for strokes
Researchers in Spain have achieved functional recovery from a stroke after implanting silk fibroin hydrogels-encapsulated stem cells in stroke mice.
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Lab-grown eggs could pave way towards new fertility treatments
Human eggs have been fully grown in a laboratory, in a move that could lead to improved fertility treatments...
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New body of resistance gene research has potential to combat superbugs
Scientists in Denmark have made it possible to rank the risk of resistance genes and predict the evolution of existing and future drugs.
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Novel curative gene therapy treatment for pulmonary fibrosis in mice
Researchers in Spain have developed a method of gene therapy that cures pulmonary fibrosis in mice by lengthening telomeres – the protective protein sections at the end of chromosomes.
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MG1 virus destroys HIV-infected cells that standard therapies can’t reach
Researchers from Canada try a new approach to eliminate dormant HIV-infected cells from the body using the MG1 virus.
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New data network for Huntington’s disease research
The first data network for this research could also be the blueprint for similar data networks for research into other conditions...
