news
Drug target discovered for pulmonary arterial hypertension
Scientists have discovered a molecular pathway that contributes to PAH development, which may lead to a new drug target for the disease.
List view / Grid view
CRISPR
article
Expert view: Call to action: establishing the protein-binding properties of oligonucleotides
The number of oligonucleotide-based platforms on the market is constantly increasing and has led to the emergence of innovative nucleic acid-based therapeutic modalities such as CRISPR-Cas, sgRNAs or mRNAs.
article
Genomics In-Depth Focus 2019
In this In-Depth Focus are articles on how genomics could revolutionise clinical treatment and an insight into the promise and pitfalls of using CRISPR.
news
Researchers reverse obesity in mice using CRISPR-Cas9
A study has used CRISPR-Cas9 to treat obesity and type 2 diabetes symptoms in mice, highlighting the potential use in humans.
news
Novel bacteria gene activation method developed
Researchers have created a new technique for activating genes using bacteria which could have therapeutic uses.
news
Breast cancer progression may be halted with CRISPR gene editing
A tumour-targeted CRISPR gene editing system encapsulated in a nanogel could halt the growth of triple-negative breast cancer.
whitepaper
eBook: Explore cells from the inside out
Modern cell biology requires a wide variety of applications to keep up with the numerous exciting directions that research takes us. Detection technologies ranging from fluorescence to cellular imaging have become common in today’s laboratories.
news
New CRISPR technique could alter the way we look at brain diseases
Researchers may have fundamentally altered the way scientists study brain diseases with new CRISPR technology.
news
CRISPR-Cas used to edit cystic fibrosis gene mutations
A research team have used genome editing to correct two of the mutations that cause cystic fibrosis.
news
Targeting a blood stem cell subset shows lasting gene editing
Scientists report how editing a portion of stem cells with CRISPR-Cas9 is sufficient for long-term reactivation of therapeutic haemoglobin.
news
Two therapeutic targets identified for lung cancer
Salk scientists discover a pair of enzymes that drive non-small-cell lung cancer by promoting inflammation which could inform the development of new therapies.
news
No-cut CRISPR could be used to treat muscular dystrophy
Researchers have successfully used a no-cut CRISPR gene editing technique as a therapy for muscular dystrophy in mice models.
news
Screening identifies gene which protects cells from Zika virus
Researchers used screening to discover genes that protect the body against the Zika virus, which could inform potential therapies against the virus.
news
Novel nanoparticles improve CRISPR gene editing
A study has used new synthetic lipids to deliver CRISPR gene editing tools into cells with up to 90 percent efficiency.
news
RNA editing capabilities expanded with new CRISPR platform
A research team have developed a new CRISPR platform called RESCUE (RNA Editing for Specific C to U Exchange).
