news
New synthetic polio vaccine candidate
A collaborative team of scientists have developed a novel synthetic vaccine with a method grown in plants that uses virus-like particles...
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Drug Development
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From cancer evolution to personalised therapies
A research team have studied how alterations in a tumour depend on each other and how these dependencies determine cancer evolution...
webinar
Skin toxicity mechanisms associated with mGluR5 negative allosteric modulators
11 August 2017 | By DiscoverX
In this webinar, DiscoverX Corporation discuss three negative allosteric modulators of metabotropic glutamate receptors, developed by Pfizer, which recently failed in preclinical development due to delayed type IV skin hypersensitivity observed in non-human primates...
news
New headquarters in Scotland strengthens drug discovery research
A provider of products and services for research in stem cells, drug discovery, human tissues and 3D cell culture has opened its European headquarters in Glasgow, UK...
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Novel immuno-oncology treatment for patients with advanced solid tumours
An experimental immuno-oncology treatment will move into early phase clinical trials for patients with advanced solid tumours...
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CRISPR identifies essential genes for cancer immunotherapy
Researchers have used CRISPR to stop the expression of individual genes in cancer cells, by knocking out every known protein-encoding gene in the human genome...
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New approach makes it easier to find novel drugs
Scientists have created a new way of screening compounds that is more sensitive than existing methods, opening up the possibility of finding new drugs...
article
CRISPR-Cas9 repairs genetic mutation in human embryos
"Well thought through and brilliantly executed" study shows different DNA-repair mechanism in embryos compared to iPSCs
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MRC forges two new deals with industry to speed drug discovery
The Medical Research Council has formed partnerships with UCB and AstraZeneca, the deals will help speed translation of discovery research into potential therapies...
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Orphan drug market to double as Pharma rethinks business model
Market intelligence suggests pharma is being forced to shift focus towards niche patient populations and orphan diseases ...
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Polyphor achieves first milestone from Wellcome for antibiotic development
Polyphor achieves first milestone from Wellcome Trust for the development of antibiotics against Gram-negative multi drug - resistant pathogens...
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Takeda launches contract R&D firm AXCELEAD
Takeda has launched a contract research and development company, AXCELEAD, at its Shonan Research Centre.
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£86 million funding announced for UK medicine and technology
The government has announced new funding of up to £86 million for UK firms to develop medical breakthroughs.
news
£8500 given to cancer research at the University of Warwick
Cancer research at the University of Warwick has received a boost thanks to the former Lord Mayor of Coventry Cllr Lindsley Harvard.
article
Development by design methodology: the key to successful manufacturing of patient-specific cell therapies
Recognised as the next wave of medicine, cell therapies have made significant strides over the last several years. But such advancements can present unique challenges, especially as more products move out of the clinic and toward commercialisation. And unlike typical pharmaceuticals, cell therapies rely heavily on the manufacturing process to…
