whitepaper
HCA: Phenotypic fingerprint of cellular function
High-content analysis app note: Phenotypic fingerprint of cellular function following gene editing by high-throughput imaging acquisition and analysis.
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Drug Discovery Processes
whitepaper
HCA Application note: New way of measuring synaptic function
High-content analysis: monitoring neurite morphology and synapse formation in primary neurons for neurotoxicity assessments and drug screening.
video
Video: High content imaging to examine RNA in cancer cells
Dr Kaylene Simpson, Peter MacCallum Cancer Center, describes their research using high content imaging to examine RNA in cancer cells.
video
Video: 3D Culture Screening
Michael Johnson and his team at Visikol talk about the work they do as a contract research organization on 3D Cell Cultures and how they utilize High-Content Analysis / Screening to generate insights.
product
Fast molecular interaction screening for all your projects
Current technologies that measure molecular interactions for drug discovery slow down and complicate screening. Dianthus is the answer to the demands for fast, non-stop, highly sensitive hit identification, hit validation and lead optimisation.
article
Drug discovery from the age of information to the age of intelligence
Data drives drug discovery, yet it continues to be among the biggest challenges faced by the industry.1 Experiments are often not repeatable and data interpretation is subject to the biases and limitations of human beings.
article
Cell line development – global market drivers, trends and its impact on improving biologics development from early phase to IND during the drug discovery process
Cell line development is a major step for examining the efficiency of drug discovery, toxicity and in vitro testing. It reduces time, effort and cost, which minimises the chance of research drugs failing at the clinical trial stage. This stage involves the production of recombinant proteins such as monoclonal antibodies,…
news
Optical imaging technique to detect tiny tumours
A method of imaging using longer wavelengths could mean that tiny tumours and clusters of cancer cells may be detected earlier than current methods allow...
webinar
Phenotypic screening using iPSC-based human disease biology
18 February 2019 | By Tecan and Ncardia
Ncardia, will discuss the application of human iPSC-derived cell-based assays and high throughput screening for drug discovery and development.
news
Developing a blood test for pain measurement
A blood test to measure pain has been developed, and could potentially aid physicians with more accuracy in diagnosis and prescriptions...
news
Development of a gel for liver cell culture on microchips
Hydrogels could be used to build organs on chips to test potential medications, with the aim that they could potentially replace animal studies...
news
Virtual drug discovery tackles unknown universe of drugs
An online compound library consisting of the structure of over a billion molecules could be the future of drug discovery...
news
Peptide research gives insight on tackling bacteria
Researchers have paved the path towards redesigning antibiotics through the alteration of the peptide assembly involved in the process...
news
Mavoglurant could improve eye gaze in fragile X patients
A first stage trial involving the experimental drug mavoglurant has shown early success in the treatment of gaze avoidance in fragile X syndrome patients...
news
Genetic study reveals possible new routes to treating osteoarthritis
Scientists discover new genes and biological pathways linked to osteoarthritis, which could help identify starting points for new medicines...
