Cancer immunotherapies may be improved with early immune response
A new mechanism has been reported for detecting foreign material during early immune responses which may help detect elusive cancers.
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A new mechanism has been reported for detecting foreign material during early immune responses which may help detect elusive cancers.
The new screening technique may enable development of novel combination-immunotherapy regimens against cancers and persistent infections.
A study has shown that a group of cells called adipose B cells can become dysfunctional with age, causing metabolic conditions such as diabetes, which has provided a drug target.
A novel CDK8 inhibitor has been developed by scientists at Ryvu Therapeutics. Dr Krzysztof Brzozka showcases this molecule and explains the R&D behind it.
A new study has discovered two enzymes which regulate a biological switch that controls the immune system, providing the potential to develop targeted therapies.
A new study has shown the specific cellular mechanisms that limit the ability of CD8 T cells to infiltrate the tumour microenvironment, which could guide new immunotherapeutic strategies in cancer.
A therapy has been developed which uses a synthetic RNA molecule developed to fight viruses to trigger an immune response against tumours in mice.
A team has used viral gene editing and CRISPR to form a system that marks tumours for destruction, potentially improving immunotherapies.
A new algorithm has been developed which personalises which cancer mutations are best targets for immunotherapy.
Researchers have discovered that a specific subset of gamma delta T cells can be found in higher numbers of breast cancer survivor tissue, indicating its role in fighting the condition.
New protein-painting technology could lead to developing cancer immunotherapy medicines that can be administered as a pill.
Monoclonal antibodies have shown great promise in the treatment of various cancers. This article discusses how therapeutic antibodies are produced and the various treatment strategies that are currently being adopted.
Researchers have discovered that B cells aid T cells in fighting cancer, which could be an area of development for immunotherapies.
A study has used a proteomic method to uncover why some melanoma tumours do not respond to immunotherapy, which could improve treatments.
Researchers have discovered the roles that immune cells play in tumour growth and breast cancer immunotherapy which could aid in drug development.