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Scientists create a nanobody that could treat Parkinson’s disease
Researchers have developed a nanobody that can penetrate the tough exterior of brain cells and untangle misshapen proteins that lead to Parkinson’s disease.
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Neurosciences
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Visualising mRNA molecules in the brains of living mice
Scientists have developed a new imaging technique that allows researchers to see gene expression and mRNA molecules in the brains of live mice in real time.
podcasts
Episode 10 – Microscopy in neuroscience with Dr Tobi Langenhan, Leipzig University & Dr Abdullah Ahmed, Leica Microsystems
Listen along as experts explore some applications of microscopy in neuroscience and discuss common challenges and considerations.
article
Using cortical spheroids to study endocannabinoids and autism spectrum disorder
The endocannabinoid system may play a role in the development of autism spectrum disorder and might be key to treating people with severe forms of the condition. In this commentary, Dr Karen Litwa, Assistant Professor at East Carolina University’s Brody School of Medicine, US explores how a bioelectronic assay is…
news
New brain mechanism involved in cocaine addiction has been identified
Researchers have found that blocking certain acetylcholine receptors in the lateral habenula made it harder to resist seeking cocaine in a rat model of addiction.
whitepaper
Product hub: A reproducible and scalable Huntington’s disease human cell model
Senior scientist Dr Tony Oosterveen discusses bit.bio’s new ioDisease Model portfolio, including new models for Huntington’s disease to help advance in vitro research and drug discovery.
article
Drug Target Review Stem Cells ebook
This ebook includes a piece by Daniel Morales- Mantilla, Dr Robin Parihar and Dr Katherine King, from Baylor College of Medicine, on a stem and progenitor cell infusion to improve the survival of mice from sepsis as well as an article by Dr Karen Litwa, East Carolina University, that explores…
news
Three distinct brain circuits in the thalamus contribute to Parkinson’s symptoms
Targeting these brain circuits could offer a new way to reverse motor dysfunction and depression in Parkinson’s disease patients.
news
Immune protein may contribute to alcoholism relapse
Scientists have found that an immune protein, CSF1, may cause anxiety during alcohol withdrawal, therefore causing relapse.
news
Scientists develop nanoparticles that can cross the blood-brain barrier
Tested using a new brain tissue model, researchers have developed nanoparticles which may be able to deliver chemotherapy drugs for glioblastoma.
news
Mouse study shows gene therapy could fight against rare disease
A new study shows that gene therapy could correct a rare creatine deficiency disorder that commonly results in intellectual disabilities, problems with speech, involuntary movements, and recurrent seizures.
news
Ultra-powerful brain scanners offer hope for treating cognitive symptoms in Parkinson’s disease
Ultra-powerful 7T MRI scanners could be used to help identify those patients with Parkinson’s disease and similar conditions most likely to benefit from new treatments for previously untreatable symptoms.
news
Animal study shows abnormal activity of brain circuit causes anorexia
Researchers have found that genetically and pharmacologically restoring the normal activity of the brain circuit improved anorexia, opening the possibility of developing a treatment strategy for affected individuals in the future.
news
Drug repurposed to boost functional recovery after a stroke
A drug currently prescribed to control seizures and reduce nerve pain may enhance recovery of movement after a stroke.
news
Stem cell replacement therapy: a potential treatment for Parkinson’s disease
In a new study, researchers describe a process for converting non-neuronal cells into functioning neurons able to restore capacities undermined by Parkinson’s destruction of dopaminergic cells.
