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Alzheimer’s disease linked to tau-mediated RNA splicing errors
A new study has shown the possibility of using RNA splicing as a potential molecular target for Alzheimer's disease.
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Neurosciences
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Researchers fail to replicate influential neuroimaging genetics study
These findings highlight the complexity of the relationship between genes and human brain function.
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Neuronal link between chronic pain and depression discovered
The mechanism in the brain connecting chronic pain and depression could lead to treatments for both, according to researchers.
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New technology developed to screen for Huntington’s treatments
Researchers have created a new technology which enabled them to discover more about the causes of Huntington’s disease and which can be used to test drugs.
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Protein target for diabetes-related Alzheimer’s identified
A study has found a protein which, when depleted, resulted in Alzheimer’s disease symptoms appearing in mouse and brain tissue models.
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New gene therapy repairs neuron stroke damage in mice
Researchers have developed a new treatment method which turned glial cells into functioning neurons in mice after stroke.
whitepaper
Whitepaper: How to address the versatile challenges of neurosciences?
Structural and functional study of the nervous system, also known as Neuroscience, is one of the scientific fields that has always crystallized the hopes and fantasy of humankind - not only interms of disease understanding and treatment but also in terms of capacity improvement.
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Researchers prevent schizophrenia progression in mice
Using mice models in late adolescence, researchers have successfully treated schizophrenia which could help develop therapies for the condition.
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Drug Target Review – Issue 3 2019
This issue includes an investigation into utilising recombinant antibodies for research, a highlight on protein design using computational methods and an examination of the advances in genomic medicine. Also in the issue are articles on next generation sequencing and upstream bioprocessing.
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Five recent Parkinson’s disease drug target discoveries
This article highlights five of the latest findings that could be used in the development or design of new therapies to treat Parkinson’s disease.
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Medical Research Council updates brain tissue database
The UK Brain Banks Network has been enhanced to include genomic data, which can be accessed by researchers worldwide.
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Scientists identify promising new target to combat Alzheimer’s disease
New research is the first to link maladaptive changes in calcium transport by mitochondria to the progression of Alzheimer's disease.
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Stem cell division in the geriatric brain blocked by signal
It has been discovered that Id4 controls whether stem cells enter cell division and may be relevant for treating neurodegenerative disease.
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Collaboration to discover MND treatments announced
MSD and the Francis Crick Institute will work together on a project to identify disease targets for motor neuron disease.
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Revealed autophagy mechanism is potential dementia target
A study has discovered the regulating process behind cell autophagy which could aid in the development of neurodegenerative disease treatments.
