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Drug Target Review – Issue 4 2019

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Posted: 10 December 2019 | | No comments yet

This issue includes a discussion on the future of high-throughput screening through collaboration, an analysis of mass spectrometry as a structural biology tool and an exploration of the challenges of hit-to-lead when researching tropical diseases. Also in the issue are articles on immuno-oncology and assays. 

Included in this issue:

  • SCREENING 
    CRISPR: kick‑starting the revolution in drug discovery
    Dr Pushpanathan Muthuirulan, Harvard University
  • ANTIBODIES
    Antibody characterisation – an essential researchers’ resource
    Dr Tara Hiltke, National Cancer Institute
  • TARGETS
    A novel approach to unravelling the mysteries of Alzheimer’s
    Professor Tuomas Knowles, University of Cambridge
    Dr Sean Devenish, Fluidic Analytics
  • PERSONALISED MEDICINE
    Getting precise: how humanised models aid in biologics drug discovery
    Paul Volden, Taconic Biosciences
  • HIT-TO-LEAD
    Transitioning novel peptide hits into lead compounds
    Steven A Trim, Venomtech
    Dr Carol M Trim, Canterbury Christ Church University

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