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B cells may travel to remote areas of the brain to improve stroke recovery
Research has found that after stroke in mice, B cells migrate to far regions of the brain that control motor functions, indicating their role in recovery.
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Protein
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Myc gene linked to alternative splicing changes in several cancers
A collaboration of academic institutions in the United States has identified a gene that is linked to alternative splicing changes that occur in several cancers.
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Lettuce used to create pulmonary arterial hypertension protein treatment
Researchers have developed a way to produce proteins from lettuce which can effectively combat pulmonary arterial hypertension in animals.
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WDR74 protein identified as lung cancer and melanoma therapeutic target
Researchers have revealed that the WDR74 protein plays a key role in lung cancer and melanoma, including metastasis, indicating it may be a potential drug target.
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ETV4 protein implicated in cancer-promoting oestrogen signalling
Research into gynaecological cancers has shown that removing the ETV4 protein from endometrial cancer cells reduces oestrogen signalling and subsequently tumour growth.
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Free radicals from immune cells cause salt-sensitive hypertension
A new study has found that in salt-sensitive hypertension, immune cells gather and release free radicals, damaging the kidneys.
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Innate protein restricts HIV replication by targeting lipid rafts
According to a new study, apolipoprotein A-I binding protein restricts HIV-1 replication by targeting lipid rafts and reducing virus-cell fusion.
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Astrocytes could be harnessed to protect motor neurons in MND
Scientists using a new motor neuron disease (MND) model have shown astrocytes may protect neurons from toxic TDP-43 protein aggregates in the early stages of disease.
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The fate of cancer is all down to particular proteins
Scientists in Japan have identified an important protein that can impact the course of cancer and its fate in the human body.
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Molecular ‘switch’ could help treat or reverse age-related diseases
A molecular 'switch' that controls the immune machinery responsible for chronic inflammation has been identified which could help treat or even reverse the development of age-related conditions like Alzheimer's, Parkinson's, cancer and diabetes.
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NLRP3 inflammasome ‘off switch’ reverses effects of chronic inflammation
Research into age-related chronic inflammatory disorders has identified an ‘off switch’ on the NLRP3 inflammasome that could be targeted in new therapies.
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Interaction site for serotonin type 3A and RIC-3 chaperone identified
To address the receptor dysfunction associated with several neurological diseases, scientists have provided novel insights into a protein-protein interaction that could lead to more effective treatments.
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New potential targeted therapy strategy for triple negative breast cancer
A study has shown that targeting the proteins mtp53 and PARP in triple negative breast cancer could inhibit tumour growth and provide a new treatment option.
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Study shows that lung tumour growth can be reduced by inhibiting p38
A new study has shown that the function of the p38 protein is related to the stimulation of cancer cell division and thus enhances tumour growth.
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Alternative splicing regulators like AKAP8 prevent cancer metastasis
A study revealed that AKAP8 promotes the alternative splicing of proteins, preventing breast cancer metastasis in animal models and could be the target of future therapies.
