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Newly engineered peptide shows long-acting efficacy against HIV
Researchers have developed a novel peptide with a prolonged half-life that has demonstrated success in rhesus monkeys and mice for inhibiting HIV infections.
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Research & Development
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Root of childhood kidney cancer discovered
The earliest genetic root of Wilms' tumour has been discovered, which could not only lead to improved treatments but to one day being able to screen for cancers like this before tumours develop.
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New protein function could be key to treatment of drug addiction
Scientists have revealed new findings about the neural circuit involved in the reward stimulus, which plays a major role in drug dependence and psychological disorders.
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The Olympus scanR high-content screening station rapidly acquires quantitative data from cell-based assays
Self-learning microscopy opens new horizons in high-content analysis and advances phenotypic screening.
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New generation of CAR T cells developed
Researchers have reprogrammed CAR T cells to prevent them becoming exhausted after prolonged activity, presenting a possible new therapy for solid tumours.
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Progression, trends and industry leaders in HIV and AIDS research
HIV is a disease still common in sub-Saharan Africa despite global research since 1982. This article delves into the trends, opportunities and key players in HIV research, exploring future possibilities for treating the disease.
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New treatment possible to tackle drug-resistant strains of TB
A new discovery could lead to the development of a drug for untreatable strains of TB, which can target uptake of the very amino acid that enables the bacteria to spread within the body.
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Two new retinal pigment epithelial cell models developed
Researchers have created two new cellular models that can be used in the study of ocular diseases and drug testing.
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Common signalling pathway across cancer and diabetes discovered by researchers
Researchers have found that the TRAP-alpha insulin biosynthesis pathway is essential in both cancer and diabetes, with a common primordial ancestor discovered in C. elegans.
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Medicine against bone disease found in Saussurea leaves
Isolated components found in the Saussurea controversa plant have antimicrobial and regenerative properties which could lead to a treatment for bone diseases.
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Vasomotion revealed as potential strategy to treat Alzheimer’s
A study has demonstrated that inducing brain vessel pulsations helps to clear substances from the brains of mice, so could be used to stop amyloid-β build up in the development of Alzheimer’s.
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Scientists discover how strep bacterium hides from the immune system
Produced by Group A Streptococcus, researchers have discovered the S protein, which binds to the red blood cell membrane to avoid being destroyed by immune cells and could be a target for anti-virulence drugs.
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Researchers must not rely on generic online searches for chemical probes, study finds
The ICR has revealed that during drug discovery, researchers should not use general search engines and vendor catalogue information to decide on their use of chemical probes.
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Protein tag developed to aid in study of the immune system
A novel approach to better understand a basic defence mechanism of the immune system has been developed using the ISG15 protein which could lead to novel antimicrobial drugs.
