Under the microscope: Improving hit discovery efficiency at Europe´s leading screening centre
Steven van Helden, Chief Technology Officer at Pivot Park Screening Centre (PPSC), relies on efficient microplate readers for effective hit discovery.
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Medical screening is a strategy used to identify the possible presence of an as-yet-undiagnosed disease in individuals without signs or symptoms.
Steven van Helden, Chief Technology Officer at Pivot Park Screening Centre (PPSC), relies on efficient microplate readers for effective hit discovery.
Researchers have discovered a particular protein that is required for enterovirus replication and survival, presenting a therapeutic target.
A new drug discovery strategy predicts the clinical actions of new compounds to promote desired clinical responses and avoid side effects.
GeneArt High-Q Strings DNA Fragments versus other suppliers’ products.
Cell line development typically includes the screening of thousands of clones to identify the few that are stable, grow as expected and produce high yields of the bioproduct.
Antisense oligonucleotides are an emerging therapeutic option for treating diseases with known genetic origin.
A significant hurdle in optimising antibody therapeutics is the screening of successive rounds of large libraries of mutant variants in order to recognise the ideal candidate.
A team from MIT sequenced bacteria samples from the digestive system which can be accessed by researchers to use in the development of treatments.
This eBook highlights a selection of 3D cell model applications as well as Molecular Devices solutions for acquiring and visualizing quantitative data.
The British Journal of Pharmacology has recommended that all studies it publishes should address sex as an experimental variable.
A research team have found a signalling pathway which plays a critical role in the maturation of periodontal ligament, providing information for the development of dental treatments.
Scientists reveal the atomic structure and regulative mechanism of the metabolic enzyme transhydrogenase.
Scientists have shown that there are molecules to remodel the gut microbiome and turn an unhealthful gut into a more healthful one for the first time.
Researchers have created a new organoid model that can be used to study systems such as the heart and the effects of drugs on these cells.
Libraries of more than 9,000 macrocyclic molecules below 1 KDa have been generated, small enough to cross cell membranes and reach targets.