news
Alzheimer’s vaccine shows promising results in bigenic mice
Researchers have created a new combination vaccine therapy that can induce strong immune responses against tau and Aβ pathologies seen in Alzheimer’s in bigenic mice.
List view / Grid view
T cells
news
New study could lead to better treatments for autoimmune diseases
A study has found a new molecular process in mice that causes autoimmune diseases and has opened avenues for developing more effective autoimmune therapies.
news
Significant breakthrough made in Zika virus vaccine development
Researchers have developed a novel T cell-based vaccine against the Zika virus that has proved effective in mouse models.
news
Previously unknown role of dendritic cells in inflammation revealed
A study has demonstrated that dendritic cells play a key role in inflammation and how TNF inhibitors can prevent them from fighting infections.
article
Using droplet digital PCR to monitor the safety of CAR T cells
CAR T-cell therapy has caused quite a stir in the immunotherapy world, but it is a process that requires precision and care. Quantitative polymerase chain reaction (qPCR) has thus far been the stalwart technique for providing a check on copy numbers, but here Ping Jin explains why droplet digital PCR…
news
New generation of CAR T cells developed
Researchers have reprogrammed CAR T cells to prevent them becoming exhausted after prolonged activity, presenting a possible new therapy for solid tumours.
news
New screening method identifies potential compounds to combat cancer
The new screening technique may enable development of novel combination-immunotherapy regimens against cancers and persistent infections.
news
microRNA could lead to new methods to treat multiple sclerosis
In a pre-clinical model of multiple sclerosis, orally treating susceptible mice with a microRNA from the diseased gut has prevented the disease.
news
Immune response against skin-living virus could prevent skin cancer
It has been discovered that papillomaviruses induce immunity that protects patients, which could lead to a novel method for preventing skin cancer using a vaccine based on T cells.
news
Protein vital for T cell formation and function revealed
Researchers have discovered a protein that is required for T cell biological processes; they have also demonstrated the mechanism behind the protein.
news
T cell immune system regulator identified by researchers
A new study has discovered two enzymes which regulate a biological switch that controls the immune system, providing the potential to develop targeted therapies.
news
Reasons why targeted immuno-oncology drugs sometimes fail discovered
A new study has shown the specific cellular mechanisms that limit the ability of CD8 T cells to infiltrate the tumour microenvironment, which could guide new immunotherapeutic strategies in cancer.
news
Global consortium formed to combat unproven cell banking services
The International Society for Cell and Gene Therapy has created a group to tackle the rising number of commercial cell bank services that are misleading patients.
news
New drug shows promise as immune therapy for cancers
A therapy has been developed which uses a synthetic RNA molecule developed to fight viruses to trigger an immune response against tumours in mice.
news
Study reveals potential of gamma delta T cells to combat breast cancer
Researchers have discovered that a specific subset of gamma delta T cells can be found in higher numbers of breast cancer survivor tissue, indicating its role in fighting the condition.
