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Imaging In-Depth Focus 2020

Posted: 26 May 2020 | | No comments yet

The articles in this in-depth focus discuss the difficulties in deciding what information to capture when imaging three-dimensional (3D) cell models and the use of non-invasive imaging techniques to discover small molecule drugs to control protein translation.

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    This content is provided to you for free thanks to the kind support of our sponsor: Molecular Devices

    In this in-depth focus:

    • Data, data and still more data: the challenges of imaging and analysing 3D cell models
      The latest generation of three-dimensional (3D) cell models offer new and exciting possibilities for pharmaceutical research. However, deciding how to capture sufficient information in the most efficient way from an experiment without making the data size overwhelming can prove challenging. Margaritha Mysior and Jeremy Simpson discuss the opportunities and challenges faced by researchers currently working in this field.
    • Seeing the light – visualising protein translation in real time
      Non-invasive imaging has played an increasing role in drug discovery and development processes. Nikki Withers spoke with Yochi Slonim, who discusses a novel technology that leverages FRET signals for the discovery of small molecule drugs that selectively control mRNA translation in a novel target space.